Results 111 to 120 of about 3,718,310 (310)

Relationship of severity of hyponatremia and adverse outcomes in children visiting the emergency department

Frontiers in Pediatrics
Mild hyponatremia is often found in patients visiting pediatric emergency departments (PEDs), but there are few large-scale studies on its association with adverse outcomes, including mortality. We conducted this study to identify the association of mild
Jisu Ryoo, Arum Choi, Hyunchul Cho, Woori Bae   +3 more
doaj   +1 more source

Management of Pregnancy in Women of Advanced Maternal Age: Improving Outcomes for Mother and Baby [Corrigendum]

International Journal of Women's Health, 2023
Glick I, Kadish E, Rottenstreich M. Int J Womens Health. 2021;13:751-759. Page 756, Autism Spectrum Disorder section, second paragraph, first sentence, the text “A large meta-analysis, including 16 epidemiological papers with 5687 autism spectrum ...
Glick I, Kadish E, Rottenstreich M
doaj  

Inhaled steroids and risk of pneumonia for chronic obstructive pulmonary disease. [PDF]

, 2014
BACKGROUND: Inhaled corticosteroids (ICS) are anti-inflammatory drugs that have proven benefits for people with worsening symptoms of chronic obstructive pulmonary disease (COPD) and repeated exacerbations.
Seniukovich, A, Alieksei Seniukovich, Kew, KM, Kayleigh M Kew   +3 more
core   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Hemoglobin and clinical outcomes of in-hospital patients with severe acute exacerbation of chronic obstructive pulmonary disease: a multicenter cohort study

Frontiers in Medicine
BackgroundHemoglobin is one of the most common laboratory tests for hospitalized patients, and both anemia and polycythemia are common comorbidities in severe acute exacerbation of chronic obstructive pulmonary disease (AECOPD). However, limited evidence
Suji Wu, Qun Yi, Qun Yi, Yuanming Luo, Hailong Wei, Huiqing Ge, Huiguo Liu, Xianhua Li, Jianchu Zhang, Pinhua Pan, Mengqiu Yi, Lina Cheng, Hui Zhou, Yongjiang Tang, Haixia Zhou   +14 more
doaj   +1 more source

Metabolomics Discovers Early-Response Metabolic Biomarkers that Can Predict Chronic Reproductive Fitness in Individual Daphnia magna

Metabolites, 2018
Chemical risk assessment remains entrenched in chronic toxicity tests that set safety thresholds based on animal pathology or fitness. Chronic tests are resource expensive and lack mechanistic insight. Discovering a chemical’s mode-of-action can in
Nadine S. Taylor, Alex Gavin, Mark R. Viant   +2 more
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Ultrasonographic assessment of thenar muscles for diagnosing sarcopenic obesity in patients with schizophrenia

Frontiers in Psychiatry
BackgroundPatients with schizophrenia have a high prevalence of sarcopenic obesity (SO) (19.2%), largely due to antipsychotic use and sedentary lifestyle.
Guoyu Yan, Huaying Ding, Xia Lin, Zhouyu Li, Lanlan Chen, Lan Xiang, Xiaoyan Chen, Youguo Tan   +7 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Prediction of adverse perinatal outcome of small-forgestational- age pregnancy using size centiles and conditional growth centiles

, 2016
Objective: To test whether adding conditional growth centiles to size centiles of estimated fetal weight (EFW) improves prediction of adverse perinatal outcome in pregnancies with or at risk of having a small-for-gestational-age (SGA) fetus.
Kiserud, Torvid, Rasmussen, Svein, Karlsen, Henriette Odland, Johnsen, S. L.   +3 more
core   +1 more source