Results 11 to 20 of about 3,485,469 (299)

Evaluating and Optimising the Retrieval of Research Evidence for Systematic Reviews of Adverse Drug Effects and Adverse Drug Reactions [PDF]

, 2013
Systematic reviews can provide timely, reliable evidence on which to make informed decisions. In order to make balanced decisions, information is not only needed on the benefits of an intervention, but also on its adverse effects.
Golder, Su
core   +6 more sources

Enhancing Communication about Paediatric Medicines: Lessons from a Qualitative Study of Parents' Experiences of Their Child's Suspected Adverse Drug Reaction [PDF]

, 2012
Background: There is little research on parents' experiences of suspected adverse drug reactions in their children and hence little evidence to guide clinicians when communicating with families about problems associated with medicines.
Smyth, RL, Young, B., Hesselgreaves, H, Munir Pirmohamed (40546), Janine Arnott (128747), Turner, M.A., Anthony J Nunn, Rosalind L. Smyth (80205), Mark A. Turner (114089), Hesselgreaves Hannah, Nunn, Anthony J., Nunn Anthony J., Nunn, Anthony J, Turner, Mark A, Matthew Peak (114087), Hesselgreaves, H., Pirmohamed, Munir, Nunn, AJ, Pirmohamed, M, Peak, M, Munir Pirmohamed, Smyth Rosalind L., Janine Arnott, Arnott Janine, Pirmohamed Munir, Nunn, A.J., Hannah Hesselgreaves (128748), Peak, M., Bridget Young (128749), Hannah Hesselgreaves, Bridget Young, Anthony J. Nunn (114088), Young, Bridget, Matthew Peak, Arnott, J, Turner Mark A., Turner, MA, Young, B, Rosalind L Smyth, Pirmohamed, M., Smyth, Rosalind L., Hesselgreaves, Hannah, Mark A Turner, Smyth, Rosalind L, Arnott, Janine, Young Bridget, Peak Matthew, Arnott, J., Smyth, R.L., Peak, Matthew, Turner, Mark A.   +50 more
core   +1 more source

Population Pharmacokinetics and Dose Optimization of Ceftazidime and Imipenem in Patients with Acute Exacerbations of Chronic Obstructive Pulmonary Disease

Pharmaceutics, 2021
Background: Ceftazidime and imipenem have been increasingly used to treat Acute Exacerbations of Chronic Obstructive Pulmonary Disease (AECOPD) due to their extended-spectrum covering Pseudomonas aeruginosa.
Thu-Minh Nguyen, Thu-Hue Ngo, Anh-Quan Truong, Dinh-Hoa Vu, Dinh-Chi Le, Ngan-Binh Vu, Tuyet-Nga Can, Hoang-Anh Nguyen, Thu-Phuong Phan, Françoise Van Bambeke, Céline Vidaillac, Quy-Chau Ngo   +11 more
doaj   +1 more source

[Vaccinovigilance: Adverse reaction reports of animal vaccines in 2020]. [PDF]

, 2021
The aim of the vigilance system in Switzerland is the evaluation and classification of reported suspected adverse reactions of immunological veterinary medicines (IVMP), including suspected lack of expected efficacy.
Zaugg, I., Ottiger, H. P.
core   +2 more sources

Drug-Related Deaths in China: An Analysis of a Spontaneous Reporting System

Frontiers in Pharmacology, 2022
Background: Adverse drug reactions with an outcome of death represent the most serious consequences and are inherently important for pharmacovigilance.
Haona Li, Jianxiong Deng, Peiming Yu, Xuequn Ren   +3 more
doaj   +1 more source

Drug-Induced Severe Cutaneous Adverse Reactions: Insights Into Clinical Presentation, Immunopathogenesis, Diagnostic Methods, Treatment, and Pharmacogenomics

Frontiers in Pharmacology, 2022
SCARs are rare and life-threatening hypersensitivity reactions. In general, the increased duration of hospital stays and the associated cost burden are common issues, and in the worst-case scenario, they can result in mortality.
Therdpong Tempark, Therdpong Tempark, Shobana John, Shobana John, Pawinee Rerknimitr, Pawinee Rerknimitr, Patompong Satapornpong, Patompong Satapornpong, Chonlaphat Sukasem, Chonlaphat Sukasem, Chonlaphat Sukasem, Chonlaphat Sukasem, Chonlaphat Sukasem, Chonlaphat Sukasem   +13 more
doaj   +1 more source

Sirt6 in pro-opiomelanocortin neurons controls energy metabolism by modulating leptin signaling

Molecular Metabolism, 2020
Objective: Sirt6 is an essential regulator of energy metabolism in multiple peripheral tissues. However, the direct role of Sirt6 in the hypothalamus, specifically pro-opiomelanocortin (POMC) neurons, controlling energy balance has not been established ...
Qin Tang, Yong Gao, Qinhui Liu, Xuping Yang, Tong Wu, Cuiyuan Huang, Ya Huang, Jinhang Zhang, Zijing Zhang, Rui Li, Shiyun Pu, Guorong Zhang, Yingnan Zhao, Jian Zhou, Hui Huang, Yanping Li, Wei Jiang, Yongsheng Chang, Jinhan He   +18 more
doaj   +1 more source

The Role of Sirt6 in Obesity and Diabetes

Frontiers in Physiology, 2018
Sirt6 is one of the sirtuin family members, a kind of NAD+-dependent histone deacetylase and ADP-ribose transferase enzyme. It has an important role in physiological and pathological processes, regulating aging, cancer, obesity, insulin resistance ...
Jiangying Kuang, Jiangying Kuang, Lei Chen, Lei Chen, Qin Tang, Qin Tang, Jinhang Zhang, Jinhang Zhang, Yanping Li, Yanping Li, Jinhan He, Jinhan He   +11 more
doaj   +1 more source

Correction: SKLB023 as an iNOS inhibitor alleviated liver fibrosis by inhibiting the TGF-beta/Smad signaling pathway [PDF]

RSC Advances
Correction for ‘SKLB023 as an iNOS inhibitor alleviated liver fibrosis by inhibiting the TGF-beta/Smad signaling pathway’ by Jinhang Zhang et al., RSC Adv., 2018, 8, 30919–30924, https://doi.org/10.1039/c8ra04955f.
Jinhang Zhang, Yanping Li, Qinhui Liu, Rui Li, Shiyun Pu, Lina Yang, Yanhuan Feng, Liang Ma   +7 more
doaj   +1 more source

Adverse reactions of Amiodarone.

Journal of geriatric cardiology : JGC, 2019
Adverse drug reaction is defined by the World Health Organization as any response to a drug that is noxious and unintended and occurs at a dose normally used in man. Older people are at elevated risk of adverse drug reactions-because of changes in pharmacodynamics, concurrent use of multiple medications and the related drug interactions.
Colunga Biancatelli, Ruben Ml, Congedo, Viviana, Calvosa, Leonardo, Ciacciarelli, Marco, Polidoro, Alessandro, Iuliano, Luigi   +5 more
openaire   +2 more sources