Results 101 to 110 of about 2,510,388 (303)

In-depth analysis of the safety of CAR-T cell therapy for solid tumors

open access: yesFrontiers in Immunology
In recent years, the rapid progress in oncology, immunology, and molecular biology has dramatically advanced cancer immunotherapy, particularly CAR-T cell therapy.
Jiayi Dong   +33 more
doaj   +1 more source

Adverse Reactions to Food Additives

open access: yesPediatric Neurology Briefs, 1987
As part of a multicentre study of food additive intolerance commissioned by the UK Ministry of Agriculture, Fisheries and Food, the prevalence of reactions to food additives was studied in a survey population by the Depts of Dermatology and Community ...
J Gordon Millichap
doaj   +1 more source

“Adverse Drug Reaction Reporting” Knowledge, Attitude and Practices of Community Pharmacy Dispensers in Dar es salaam, Tanzania [PDF]

open access: yes, 2011
Under reporting of adverse drug reactions (ADRs) by healthcare personnel is a common problem of many Pharmacovigilence programs. Lack of involvement of healthcare professionals such as pharmacists and other pharmaceutical dispensers has been cited as one
Shimwela, Grace Mng’ong’o
core  

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand   +5 more
wiley   +1 more source

Factors Associated With the Rising Trend in Self‐Reported Cognitive Disability Among U.S. Adults Aged 18–39 From 2013–2024

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Building on our prior Behavioral Risk Factor Surveillance System analysis identifying adults aged 18–39 as the primary driver of the national increase in self‐reported cognitive disability, we examined factors associated with this rise using 2013–2024 U.S. BRFSS data. Methods We analyzed U.S.
Adam de Havenon   +9 more
wiley   +1 more source

Patient knowledge on reporting adverse drug reactions in Poland

open access: yes, 2016
Anna Staniszewska,1 Marta Dąbrowska-Bender,2 Dominik Olejniczak,2 Aneta Duda-Zalewska,2 Magdalena Bujalska-Zadrożny3 1Department of Experimental and Clinical Pharmacology, 2Department of Public Health, 3Department of Pharmacodynamics, Medical University
Duda-Zalewska A   +4 more
core  

Adverse drug events resulting from use of drugs with sulphonamide-containing anti-malarials and artemisinin-based ingredients: findings on incidence and household costs from three districts with routine demographic surveillance systems in rural Tanzania. [PDF]

open access: yes, 2013
BACKGROUND: Anti-malarial regimens containing sulphonamide or artemisinin ingredients are widely used in malaria-endemic countries. However, evidence of the incidence of adverse drug reactions (ADR) to these drugs is limited, especially in Africa, and ...
Abdulnoor M Kabanywanyi   +19 more
core   +1 more source

Predictive Value of Composite Inflammatory Markers for Stroke Prognosis: A Prospective Cohort Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Novel composite inflammatory markers' role in stroke prognosis is understudied, and the best predictor is unclear, requiring further exploration. Objectives This study aimed to systematically evaluate the associations of 6 novel composite inflammatory markers on stroke prognosis.
Bing Wu   +7 more
wiley   +1 more source

A Prospective Analysis of Adverse Drug Reactions in a South Indian Hospital [PDF]

open access: yes, 2009
Adverse drug reactions are a great cause of concern to the medical profession, the patients and the pharmaceutical industry. However ADR reporting and monitoring is yet to catch up in India.
Pereira, P, Padmaja, U, Adhikari, P
core  

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem   +9 more
wiley   +1 more source

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