Results 101 to 110 of about 179,801 (303)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Powered paragliders in biodiversity exploration Uso de paramotores para explorar la biodiversidad

open access: yesRevista Mexicana de Biodiversidad, 2006
Transportation technology is key to biodiversity exploration, and innovations often provide new access to biological questions. Powered paragliders are very small powered aircraft developed for recreational use that have great potential for use by ...
Mark E. Olson
doaj  

Advanced geometrical constructs in a Pueblo ceremonial site, c 1200 CE

open access: yes, 2017
Summer 2015 marked the 100th anniversary of the excavation by J.W. Fewkes of the Sun Temple in Mesa Verde National Park, Colorado, an ancient complex prominently located atop a mesa, constructed by the ancestral Pueblo peoples approximately 800 years ago.
Towers, Sherry
core   +1 more source

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

open access: yesFEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani   +7 more
wiley   +1 more source

Trends of the elephant population in northern Botswana from aerial survey data

open access: yesPachyderm, 1998
Summarizes methods and results of aerial surveys since 1973, and presents a history of the elephant population in Botswana with estimates of recent trends provided by survey data.
Deborah Gibson   +2 more
doaj   +1 more source

Infrared investigations Status report, 1 Jul. - 30 Sep. 1966 [PDF]

open access: yes
Aerial infrared surveys using infrared scanners and ...
Moxham, R. M.
core   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

open access: yesFEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

open access: yesFEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso   +4 more
wiley   +1 more source

Some aspects of the ecology of the leatherback turtle Dermochelys coriacea at Laguna Jalova, Costa Rica [PDF]

open access: yes, 1987
The ecology and reproductive biology of the leatherback turtle (Dennochelys coriacea) was studied on a high-energy nesting beach near Laguna Jalova, Costa Rica, between 28 March and 8 June 1985.
Hirth, Harold F., Ogren, Larry H.
core  

Selous aerial survey 1981

open access: yesPachyderm, 1983
Summarizes results from the 1981 Selous aerial survey, which included about 35% of the Reserve, and compares them to the 1976 data. Elephant numbers seem to have remained relatively stable with the 1976 estimate being 82,628 +/- 17% and the 1981 one being 85,504 +/- 12%.
openaire   +2 more sources

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