Results 41 to 50 of about 108,240 (318)

Patient‐Level Barriers and Facilitators to Inpatient Physical Therapy in Adolescents and Young Adults With a Hematological Malignancy: A Qualitative Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Despite their increased risk for functional impairment resulting from cancer and its treatments, few adolescents and young adults (AYAs) with a hematological malignancy receive the recommended or therapeutic dose of exercise per week during inpatient hospitalizations.
Jennifer A. Kelleher, Jennifer L. Bernstein, Katia M. Crisler, Julia K. Herriott, Kimberly L. Klages, Robin E. Norris, Mariann L. Strenk, Sarah E. Bills, Meghan E. McGrady   +8 more
wiley   +1 more source

The Time Course of Oxygen Uptake, Aerobic Capacity and Emg during Two Months of Moderate Interval Endurance Training (A Case Study)

Baltic Journal of Sport and Health Sciences, 2018
Research  background  and  hypothesis. The  low-moderate-intensity  continuous endurance training improved body composition, aerobic capacity and overall health-related parameters in healthy persons.
Sandra Raubaitė, Neringa Baranauskienė, Arvydas Stasiulis   +2 more
doaj   +1 more source

Exercise Interventions in Children, Adolescents and Young Adults With Paediatric Bone Tumours—A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Bone tumours present significant challenges for affected patients, as multimodal therapy often leads to prolonged physical limitations. This is particularly critical during childhood and adolescence, as it can negatively impact physiological development and psychosocial resilience.
Jennifer Queisser, Claire Laurie, Teresa Schmidt, Irene von Luettichau, Peter Bekkering, Sabine Kesting   +5 more
wiley   +1 more source

Associations between anthropometric characteristics and physical performance in male law enforcement officers: A retrospective cohort study [PDF]

, 2016
BACKGROUND: Police officers are often required to undertake physically demanding tasks, like lifting, dragging and pursuing a suspect. Therefore, physical performance is a key requirement. METHODS: Retrospective data for 76 male police officers (mean age 
Dawes, James Jay, Orr, Robin Marc, Pope, Rodney, Siekaniec, Claire Louise, Vanderwoude, Andrea Annie   +4 more
core   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Pre-cooling for endurance exercise performance in the heat: a systematic review. [PDF]

, 2012
PMCID: PMC3568721The electronic version of this article is the complete one and can be found online at: http://www.biomedcentral.com/1741-7015/10/166. This is an Open Access article distributed under the terms of the Creative Commons Attribution License
AC Burton, B Nielsen, C Tyler, CG Maher, Christian Barton, CR Abbiss, D Kay, DJ McCann, DT Lee, DT Martin, Dylan Morrissey, F Marino, FE Marino, GA Selkirk, GF Ranalli, H Hasegawa, H Olschewski, J Booth, J González-Alonso, J Webster, JA Sterne, JD Cotter, JD MacDougall, JJ Peiffer, K Brück, M Cabanac, M Gleeson, M Ihsan, MA Febbraio, MA Merrick, MJ Price, MJ Quod, MJ Quod, ML Ross, MN Sawka, MN Sawka, N Bogerd, N El Helou, NA de Morton, Nicola Maffulli, P Sedgwick, Paul R Jones, R Duffield, R Eccles, R Siegel, R Siegel, RJ Maughan, RM Smith, S Uckert, SA Arngrïmsson, SA Tenaglia, SD Galloway, Stephanie Hemmings, TD Noakes, TL Vanden Hoek, TT Romet, V Hessemer, V Schmidt   +57 more
core   +2 more sources

Prolonged Heat Acclimation and Aerobic Performance in Endurance Trained Athletes [PDF]

Frontiers in Physiology, 2019
Heat acclimation (HA) involves physiological adaptations that directly promote exercise performance in hot environments. However, for endurance-athletes it is unclear if adaptations also improve aerobic capacity and performance in cool conditions, partly because previous randomized controlled trial (RCT) studies have been restricted to short ...
C. Jacob Mikkelsen, Nicklas Junge, Jacob F. Piil, Nathan B. Morris, Laura Oberholzer, Christoph Siebenmann, Christoph Siebenmann, Carsten Lundby, Carsten Lundby, Lars Nybo   +9 more
openaire   +6 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Effects of creatine monohydrate supplementation on simulated soccer performance [PDF]

, 2014
Purpose: To determine the effects of acute short-term creatine (Cr) supplementation on physical performance during a 90-min soccer-specific performance test. Methods: A double-blind, placebo-controlled experimental design was adopted during which 16 male
Abt, Grant, Kilding, Andrew E., Williams, Jeremy   +2 more
core   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source