Results 51 to 60 of about 198,009 (143)

Microbiome and aging: Trajectories of microbiome age across human ecosystems and their systemic effects

iMeta, Volume 5, Issue 4, August 2026.
Microbiome age (MA) has emerged as an innovative biomarker of biological aging, reflecting host aging trajectories through dynamic alterations in microbial composition, function, and host–microbe interactions across multiple body ecosystems. Diverse computational strategies—including traditional machine learning, deep learning, and multi‐omics ...
Zhexin Ni, Jiaojiao Xie, Zhichun Zhang, Keming Zhang, Jie Ding, Mingyang Chang, Ying Su, Yunan Zhang, Mingfei Yao, Chengyuan Wang, Yan Yan, Wenjie Fang, Hainv Gao, Xuecong Tian, Yangshuo Li, Xinlin Zhu, Wen Zhang, Wanqing Liao, Gaoyuan Xu, Guojing Chen, Xiaoyi Lv, Chaoqin Yu, Weihua Pan, Vadim Molodtsov, Lanjuan Li, Yue Gao, Wei Zhou   +26 more
wiley   +1 more source

Effects of the HDAC6/8 Inhibitor MC1568, Alone and in Combination With Fluconazole, in Non‐Albicans Candida Species Infections

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
This study explores new antifungal strategies to combat non‐albicans Candida species. We tested clinically approved HDAC inhibitors—Vorinostat, Romidepsin, Tucidinostat—and the HDAC6/8‐selective MC1568, alone and with Fluconazole. The Fluconazole/MC1568 combination significantly enhanced antifungal activity and reduced biofilm formation.
Andrea Giammarino, Chiara Lambona, Alessia Raucci, Giovanna Simonetti, Salvatore Macrì, Angela Iuzzolino, Daniela Trisciuoglio, Sergio Valente, Gustavo Giusiano, Letizia Angiolella, Antonello Mai   +10 more
wiley   +1 more source

The Role of Enterococcus faecium in the Synergistic Clearance of High‐Risk HPV: A Clinical Study on Cervicovaginal Microbiota Regulation

Cancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Background Persistent infection with high‐risk human papillomavirus (HR‐HPV) is defined as the principal cause of cervical cancer. Given the important role of cervicovaginal microbiota in HPV acquisition and disease progression, this study aims to evaluate the clinical efficacy of the probiotic Enterococcus faecium (E.
Jun Yang, Mengya Gao, Danfeng Wang, Ziwei Li, Sijing Li, Min Zhou, Li‐Na Hu   +6 more
wiley   +1 more source

Aetiological Pattern of Vulvovaginal Infections in Asymptomatic and Symptomatic HIV Seropositive Women on Antiretroviral Therapy [PDF]

Journal of Clinical and Diagnostic Research, 2020
Introduction: Human Immunodeficiency Virus (HIV) causes severe public health problems. Despite the use of Highly Active Antiretroviral Therapy (HAART), opportunistic infections remain a serious problem in HIV infection.
Divya Garg, Shukla Das, AG Radhika, Alpana Raizada, Vishal Gaurav, Rituparna Saha, Siddharth Sonthalia, Richa Anjleen Tigga   +7 more
doaj   +1 more source

Prevalence of Bacterial Vaginosis and Associated Risk Factors among Women Complaining of Genital Tract Infection

International Journal of Microbiology, 2017
Background. Bacterial vaginosis is a global concern due to the increased risk of acquisition of sexually transmitted infections. Objectives. To determine the prevalence of bacterial vaginosis and bacteria causing aerobic vaginitis. Methods.
Adane Bitew, Yeshiwork Abebaw, Delayehu Bekele, Amete Mihret   +3 more
doaj   +1 more source

Preliminary Identification of the Aerobic Cervicovaginal Microbiota in Mexican Women With Cervical Cancer as the First Step Towards Metagenomic Studies

Frontiers in Cellular and Infection Microbiology, 2022
Cervical cancer (CC) is considered a public health problem. Recent studies have evaluated the possible relationship between the cervicovaginal microbiome and gynecologic cancer but have not studied the relationship between aerobic bacterial communities ...
Gauddy Lizeth Manzanares-Leal, Jaime Alberto Coronel-Martínez, Miguel Rodríguez-Morales, Iván Rangel-Cuevas, Lilia Patricia Bustamante-Montes, Horacio Sandoval-Trujillo, Ninfa Ramírez-Durán   +6 more
doaj   +1 more source

Recurrent vaginitis: Diagnostic and treatment difficulties

, 2020
Background. Recurrent vaginitides, lower urogenital tract diseases occurring at a frequency of 8-30%, are related to diagnostic and treatment difficulties. Case report.
Solovyeva A.V.
core   +2 more sources

Living Hydrogels: Harnessing Microorganism–Material Synergy for Next‐Generation Therapeutics

Advanced Science, Volume 13, Issue 25, 4 May 2026.
 . ABSTRACT Microorganism‐based therapies, particularly those utilizing probiotics, have emerged as a powerful biomedical strategy owing to their inherent living functionalities. These living systems can dynamically interact with host environments and self‐regulate their activity, offering superior adaptability, prolonged functionality, and ...
Shuifang Mao, Bingyao Bai, Xingqian Ye, Yiliang Lin   +3 more
wiley   +1 more source

Candida glabrata Isolated From Tubo‐Ovarian Abscess Cultures in Two Immunocompetent Patients

Clinical Case Reports, Volume 14, Issue 5, May 2026.
Persistent 7.3 × 5.8 cm TOA unresponsive to 4 weeks of antibiotic treatment and percutaneous drainage, growing Candida glabrata on cultures. ABSTRACT In this clinical case report, we present two immunocompetent patients with tubo‐ovarian abscesses (TOAs) that were positive for Candida glabrata.
Marlee Hirsch, Rosalie DePaola, Jordan Eisenberg, Amir Shay, Tyler M. Moore, Adi Katz, Richard A. Stein   +6 more
wiley   +1 more source

Aerobic vaginitis – diagnostic problems and treatment [PDF]

, 1970
The diagnostic criteria and treatment of aerobic vaginitis – AV – have been summarized in this review. An expansion of mixed aerobic microflora, especially Group B Streptococcus - GBS, Escherichia coli – E. coli, Enterococcus spp., and the development of
Wojciechowska-Wieja, Anna, Romanik, Małgorzata, Martirosian, Gayane   +2 more
core