Results 61 to 70 of about 187,730 (163)

Effects of the HDAC6/8 Inhibitor MC1568, Alone and in Combination With Fluconazole, in Non‐Albicans Candida Species Infections

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
This study explores new antifungal strategies to combat non‐albicans Candida species. We tested clinically approved HDAC inhibitors—Vorinostat, Romidepsin, Tucidinostat—and the HDAC6/8‐selective MC1568, alone and with Fluconazole. The Fluconazole/MC1568 combination significantly enhanced antifungal activity and reduced biofilm formation.
Andrea Giammarino, Chiara Lambona, Alessia Raucci, Giovanna Simonetti, Salvatore Macrì, Angela Iuzzolino, Daniela Trisciuoglio, Sergio Valente, Gustavo Giusiano, Letizia Angiolella, Antonello Mai   +10 more
wiley   +1 more source

The Role of Enterococcus faecium in the Synergistic Clearance of High‐Risk HPV: A Clinical Study on Cervicovaginal Microbiota Regulation

Cancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Background Persistent infection with high‐risk human papillomavirus (HR‐HPV) is defined as the principal cause of cervical cancer. Given the important role of cervicovaginal microbiota in HPV acquisition and disease progression, this study aims to evaluate the clinical efficacy of the probiotic Enterococcus faecium (E.
Jun Yang, Mengya Gao, Danfeng Wang, Ziwei Li, Sijing Li, Min Zhou, Li‐Na Hu   +6 more
wiley   +1 more source

The Threat of Aerobic Vaginitis to Pregnancy and Neonatal Morbidity [PDF]

, 2019
Aerobic vaginitis (AV) is an endogenous opportunistic infection brought about by the disruption of the normal vaginal microbiota. Its early diagnosis and treatment during pregnancy may reduce the risk of negative pregnancy outcomes.
Africa, Charlene W.J., Kaambo, Eveline
core   +1 more source

Preliminary Identification of the Aerobic Cervicovaginal Microbiota in Mexican Women With Cervical Cancer as the First Step Towards Metagenomic Studies

Frontiers in Cellular and Infection Microbiology, 2022
Cervical cancer (CC) is considered a public health problem. Recent studies have evaluated the possible relationship between the cervicovaginal microbiome and gynecologic cancer but have not studied the relationship between aerobic bacterial communities ...
Gauddy Lizeth Manzanares-Leal, Jaime Alberto Coronel-Martínez, Miguel Rodríguez-Morales, Iván Rangel-Cuevas, Lilia Patricia Bustamante-Montes, Horacio Sandoval-Trujillo, Ninfa Ramírez-Durán   +6 more
doaj   +1 more source

Living Hydrogels: Harnessing Microorganism–Material Synergy for Next‐Generation Therapeutics

Advanced Science, Volume 13, Issue 25, 4 May 2026.
 . ABSTRACT Microorganism‐based therapies, particularly those utilizing probiotics, have emerged as a powerful biomedical strategy owing to their inherent living functionalities. These living systems can dynamically interact with host environments and self‐regulate their activity, offering superior adaptability, prolonged functionality, and ...
Shuifang Mao, Bingyao Bai, Xingqian Ye, Yiliang Lin   +3 more
wiley   +1 more source

A study of aerobic bacterial pathogens associated with vaginitis in reproductive age group women (15-45 years) and their sensitivity pattern [PDF]

, 2017
Background: Aerobic vaginitis (AV) is caused by a displacement of the healthy vaginal Lactobacillus species with aerobic pathogens such as Enterococcus faecalis, Escherichia coli and Staphylococcus aureus that triggers a localized vaginal inflammatory ...
K. T., Sangeetha, C. L., Vasudha, Golia, Saroj   +2 more
core   +1 more source

Prevalence of Bacterial Vaginosis and Associated Risk Factors among Women Complaining of Genital Tract Infection

International Journal of Microbiology, 2017
Background. Bacterial vaginosis is a global concern due to the increased risk of acquisition of sexually transmitted infections. Objectives. To determine the prevalence of bacterial vaginosis and bacteria causing aerobic vaginitis. Methods.
Adane Bitew, Yeshiwork Abebaw, Delayehu Bekele, Amete Mihret   +3 more
doaj   +1 more source

Candida glabrata Isolated From Tubo‐Ovarian Abscess Cultures in Two Immunocompetent Patients

Clinical Case Reports, Volume 14, Issue 5, May 2026.
Persistent 7.3 × 5.8 cm TOA unresponsive to 4 weeks of antibiotic treatment and percutaneous drainage, growing Candida glabrata on cultures. ABSTRACT In this clinical case report, we present two immunocompetent patients with tubo‐ovarian abscesses (TOAs) that were positive for Candida glabrata.
Marlee Hirsch, Rosalie DePaola, Jordan Eisenberg, Amir Shay, Tyler M. Moore, Adi Katz, Richard A. Stein   +6 more
wiley   +1 more source

Aerobic vaginitis – diagnostic problems and treatment [PDF]

, 1970
The diagnostic criteria and treatment of aerobic vaginitis – AV – have been summarized in this review. An expansion of mixed aerobic microflora, especially Group B Streptococcus - GBS, Escherichia coli – E. coli, Enterococcus spp., and the development of
Wojciechowska-Wieja, Anna, Romanik, Małgorzata, Martirosian, Gayane   +2 more
core  

Evaluation of the effectiveness of dequalinium chloride vaginal tablets in aerobic vaginitis: A placebo-controlled study

Eastern Journal of Medical Sciences, 2021
Background: Aerobic vaginitis is a disturbance of vaginal homeostasis caused by the colonization of enteric bacteria. They are not clinically well-defined and do not have standard treatment regimes. Hence, the present study was conducted to evaluate the effectiveness of dequalinium chloride topical vaginal administration in aerobic vaginitis in a ...
Sibel Ejder Tekgunduz, Ferit Saracoglu
openaire   +2 more sources