Results 71 to 80 of about 198,009 (143)

Next‐Generation Sequencing in Infectious‐Disease Diagnostics: Economic, Regulatory, and Clinical Pathways to Adoption

open access: yesMicrobiologyOpen, Volume 14, Issue 6, December 2025.
Next‐generation sequencing (NGS) is poised to transform infectious‐disease diagnostics. Falling per‐sample costs, new CPT codes and FDA pathways, and 24‐h, multiplexed resistome reports converge to deliver faster, evidence‐based therapy and stronger surveillance. Our roadmap links the economic, regulatory, and clinical pillars to accelerate routine NGS
John Osei Sekyere
wiley   +1 more source

Stability and performance of two GSBR operated in alternating anoxic/aerobic or anaerobic/aerobic conditions for nutrient removal [PDF]

open access: yes, 2012
Two granular sludge sequencing batch reactors (GSBR) with alternating anoxic/aerobic (R1) and anaerobic/aerobic (R2) conditions were operated with a 4-carbon-source synthetic influent. The physical properties of the granular sludge were very good (SVI≈20
Manas, Angela   +5 more
core   +1 more source

Non‐albicans Candida in Vulvovaginal Candidiasis: Antifungal Resistance and Expression of ERG11, CDR1, CDR2, and MDR1 Genes

open access: yesMicrobiologyOpen, Volume 14, Issue 6, December 2025.
The rise in azole resistance among Nakaseomyces glabratus and Pichia kudriavzevii presents a growing public health challenge. These results indicate that even in cases where an isolate is classified as susceptible by drug susceptibility testing, elevated gene expression may persist, and treatment should not be discontinued.
Fatemeh Zahra Ranjbar Golafshani   +3 more
wiley   +1 more source

A persistent hymen resulting in an open cervix but closed pyometra and pyocolpos in a mixed‐breed female domestic dog

open access: yesVeterinary Record Case Reports, Volume 13, Issue 4, December 2025.
Abstract A rescued mixed‐breed (Africanis type), entire, female dog, approximately 2 years old, with an unknown history, presented with a prominent perineal swelling between the anus and vulva. Ultrasound identified it as a fluid‐filled structure, and an aspirate revealed an exudate consisting of degenerate neutrophils, bacterial cocci and rods.
Taylor June Kruger   +4 more
wiley   +1 more source

Antimicrobial prescribing guidelines for horses in Australia

open access: yesAustralian Veterinary Journal, Volume 103, Issue 12, Page 781-889, December 2025.
The growing problem of antimicrobial resistance also affects equine veterinarians with increasing frequency. Antimicrobial stewardship and responsible prescribing are essential for a future in which effective antimicrobials are available, as it is unlikely that new antimicrobials will become available for use in horses.
L Hardefeldt   +18 more
wiley   +1 more source

Hasil Perbandingan Kerapatan Dosis Bakteri Streptoccocus agalactiae Terhadap Keberhasilan Pembuatan Tikus Model Aerobic Vaginitis

open access: yes
Aerobic vaginitis merupakan kondisi infeksi pada vagina, yang merangsang respon inflamasi yang tinggi, dan sulit diobati akibat meningkatnya masalah resistensi antibiotika.
Adar, Olivera Agnes   +2 more
core   +3 more sources

Proteomic Profiling of Bacterial Extracellular Vesicles for Exploring Ovarian Cancer Biomarkers

open access: yesJournal of Extracellular Biology, Volume 4, Issue 10, October 2025.
ABSTRACT Extracellular vesicles (EVs) are present in body fluids and act as disease biomarkers. Emerging evidence has proven that EVs are released not only from mammalian cells but also from bacteria. Ovarian cancer has a dismal prognosis because of difficulties in early detection.
Eri Asano‐Inami   +11 more
wiley   +1 more source

Polymicrobial Biofilms: Interkingdom Interactions, Resistance and Therapeutic Strategies

open access: yesMicrobial Biotechnology, Volume 18, Issue 8, August 2025.
Polymicrobial biofilms: interkingdom interactions, resistance and therapeutic stratergies. This review highlights the heightened drug resistance and complexity of polymicrobial biofilms, emphasising their persistence over mono‐species counterparts. It explores microbial interactions, resistance mechanisms and emerging strategies, including metabolite ...
Paramasivam Nithyanand   +3 more
wiley   +1 more source

Effects of Lactobacillus rhamnosus and Lactobacillus acidophilus on bacterial vaginal pathogens

open access: yesInternational Journal of Immunopathology and Pharmacology, 2017
The human vagina is colonized by a variety of microbes. Lactobacilli are the most common, mainly in healthy women; however, the microbiota composition can change rapidly, leading to infection or to a state in which potential pathogenic microorganisms co ...
Lucia Bertuccini   +3 more
doaj   +1 more source

Human Cervix Chip: A Preclinical Model for Studying the Role of the Cervical Mucosa and Microbiome in Female Reproductive Health

open access: yesBioEssays, Volume 47, Issue 7, July 2025.
The microfluidic Cervix Chip is an in vitro model of the human cervix lined by cervical epithelium interfaced with stromal cells cultured under dynamic flow that represents a new preclinical platform for studying mucosal immunity, host‐microbiome interactions, infections, fertility, and pregnancy health.
Zohreh Izadifar   +4 more
wiley   +1 more source

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