Results 71 to 80 of about 10,509 (314)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Unstructured mesh algorithms for aerodynamic calculations [PDF]
, 2008 The use of unstructured mesh techniques for solving complex aerodynamic flows is discussed. The principle advantages of unstructured mesh strategies, as they relate to complex geometries, adaptive meshing capabilities, and parallel processing are emphasized.
openaire +1 more source
A numerical study on aerodynamic resonance in transonic separated flow
, 2009 An ongoing numerical investigation of unsteady shock/boundary layer interaction on a 2-d supercritical airfoil in transonic flow is presented. Initially, the finitevolume URANS solver DLR-TAU is used to simulate self-sustained periodic shock oscillations
Nitzsche, Jens
core
Integration of CFD tools in aerodynamic design of contra-rotating propellers blades [PDF]
, 2011 A strategy for Contra-Rotating Open Rotors blades design is presented. It is based on several analytical or CFD tools with increasing levels of accuracy. A preliminary design is made with a lifting-line code. These first geometries are then validated and
Béchet, Sylvain +3 more
core
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
PrandtlPlane High–Lift System Preliminary Aerodynamic Design
, 2006 An analysis of low-speed aerodynamics for an unconventional aircraft configuration has been carried out. This configuration, named Prandtlplane, implements Prandtl's Best Wing System for low induced drag.
Iezzi, Giuseppe
core
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
CALCULATION OF ROCKET NOSE FAIRING SHELLS AERODYNAMIC CHARACTERISTICS
Научный вестник МГТУ ГА, 2018 The aerodynamic characteristics of the detachable elements of transport systems are introduced, they allow to calculate the trajectories of these elements after their separation and determine the size of elements impact areas.
V. T. Kalugin +2 more
doaj +1 more source
Three dimensional frequency-domain solution method for unsteady turbomachinery flows [PDF]
, 2003 The three-dimensional calculation of unsteady flows is increasingly gaining importance in the prediction of turbomachinery flow problems. A three-dimensional Euler/Navier-Stokes solver incorporating the time-linearized method and the nonlinear harmonic ...
Vasanthakumar, Parthasarathy
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source