Results 81 to 90 of about 10,509 (314)

Aerodynamic design optimization using flow feature parameterization

open access: yes, 2007
Design optimization methods using high-fidelity computational fluid dynamics simulations are becoming increasingly popular in the area of aerodynamic design, sustaining the desire to make these methods more computationally efficient.
Barrett, Thomas Robin
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Research on the Impact of the Slider on the Aerodynamic Characteristics of a Terrestrial–Aerial Spherical Robot

open access: yesActuators
This research introduces the first design concept for a ducted coaxial-rotor amphibious spherical robot (BYQ-A1), utilizing the principle of variable mass control.
Dongshuai Huo   +3 more
doaj   +1 more source

The feasibility of a road vehicle mounted aerodynamic testing apparatus

open access: yes, 2011
A ground vehicle mounted aerodynamic testing apparatus has been identified as a candidate concept for a low-cost alternative to traditional techniques.
Adams, Jordan
core  

Experimental validation of unsteady models for fluid structure interaction: Application to yacht sails and rigs [PDF]

open access: yes, 2012
• We present full scale measurements on a yacht sailing upwind in moderate head swell • We highlight the unsteadiness of the loads : peaks may be twice the mean value • The dynamic behavior differs from the steady state : hysteresis loop • Experimental ...
AUGIER, Benoit   +3 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Aerodynamic analysis of a light aircraft at different design stages [PDF]

open access: yesFME Transactions, 2014
During the evolution of an airplane aerodynamic design, proper calculation methods and software tools should be utilized, which correspond to the airplane category and project development level.
Kostić Ivan A.   +2 more
doaj  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Study on Aerodynamic Characteristics of Cyclorotor with Blade Solid and Distance between Axis

open access: yesHangkong gongcheng jinzhan, 2019
The accuracy of the Sliding grid calculation method applied to the aerodynamics calculation is verified with an example in hovering, then, the aerodynamic parameters of cyclorotor with different radius, chord and number of blades are studied, and the ...
Feng Xubi   +3 more
doaj   +1 more source

Aerodynamic analysis and optimisation of a servo-controlled aileron

open access: yes, 2011
Includes bibliographical references (leaves 185-190).The pressure for the airline industry to reduce its consumption of fuel is mounting. It has been conjectured that smart materials could be employed to control the aileron deflections via the tab, using
Day, Chris
core  

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