Results 71 to 80 of about 9,635,660 (350)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
(Un)markedness of trills : the case of Slavic r-palatalisation [PDF]
, 2010 This paper evaluates trills [r] and their palatalized counterparts [rj] from the point of view of markedness. It is argued that [r]s are unmarked sounds in comparison to [rj]s which follows from the examination of the following parameters: (a) frequency ...
Zygis, Marzena
core
Piezoelectric vibration energy harvesting from airflow in HVAC (Heating Ventilation and Air Conditioning) systems [PDF]
, 2017 This study focuses on the design and wind tunnel testing of a high efficiency Energy Harvesting device, based on piezoelectric materials, with possible applications for the sustainability of smart buildings, structures and infrastructures.
Bontempi, Franco +2 more
core +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Investigation of the aerodynamic characteristics of a lifting body in ground proximity [PDF]
, 2016 The use of cambered hull shapes in the next generation of lighter-than-air vehicles to enhance aerodynamic performance, together with optimized take-off manoeuvre profiles, will require a more detailed understanding of ground proximity effects for such
Garry, Kevin P. +2 more
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
The role of time-history effects in the formulation of the aerodynamics of aircraft dynamics [PDF]
The scope of any aerodynamic formulation proposing to embrace a range of possible maneuvers is shown to be determined principally by the extent to which the aerodynamic indicial response is allowed to depend on the past motion.
Schiff, L. B., Tobak, M.
core +1 more source
Interactional aerodynamics and acoustics of a propeller-augmented compound coaxial helicopter [PDF]
, 2008 The aerodynamic and acoustic characteristics of a generic hingeless coaxial helicopter with a tail-mounted propulsor and stabiliser have been simulated using Brown's Vorticity Transport Model.
Brown, Richard +3 more
core
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Model-following control for an oblique-wing aircraft [PDF]
A variable-skew oblique wing offers a substantial aerodynamic performance advantage for aircraft missions that require both high efficiency in subsonic flight and supersonic dash or cruise.
Alag, G. S. +4 more
core +1 more source