Results 101 to 110 of about 147,888 (314)

Aerodynamic characteristics and genesis of aggregates at Sakurajima Volcano, Japan. [PDF]

open access: yesSci Rep, 2022
Vecino MCD   +9 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Optimizing the Aerodynamic Performance of a Duct–Rotor System for Drones: A Comprehensive Study on the Coupled Parameters

open access: yesDrones
The integrated ducted structure significantly enhances the aerodynamic performance of the duct–rotor system, reducing noise and enhancing rotor safety. However, in the duct–rotor system, the coupled parameters of the rotor and the duct are crucial to its
Wei Wei   +8 more
doaj   +1 more source

Choosing the aerodynamic configuration of a subsonic cruise missile

open access: yesВестник Самарского университета: Аэрокосмическая техника, технологии и машиностроение, 2019
The paper presents a comparison of two aerodynamic configurations of subsonic cruise missiles, characterized by the use of swept-back and forward-swept wings. The results of wind tunnel tests with the use of an automated measurement system characterizing
M. A. Kovalev, A. N. Nikitin
doaj   +1 more source

A review of the planform effects on the low-speed aerodynamic characteristics of triangular and modified triangular wings [PDF]

open access: yes
Planform effects on low speed aerodynamic characteristics of triangular and modified triangular ...
Razak, K., Snyder, M. H., Jr.
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

The effect of rapid maxillary expansion on the upper airway's aerodynamic characteristics. [PDF]

open access: yesBMC Oral Health, 2021
Feng X   +4 more
europepmc   +1 more source

Subsonic longitudinal aerodynamic characteristics of a 40 deg semiapex angle conical reentry configuration [PDF]

open access: yes
Subsonic longitudinal aerodynamic characteristics of semiapex angle conical reentry ...
Phillips, W. P.
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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