Results 81 to 90 of about 38,021 (315)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Effect of cross wind on aerodynamic coefficients of ground vehicles.

open access: yes, 2009
The present work investigates the variation of aerodynamic coefficients with the change in the angle of flow. A mathematical equation has been developed for predicting the aerodynamic coefficients, when a vehicle is subjected to crosswind.
Malviya, Vihar   +2 more
core  

A new method for predicting the vortex induced aerodynamic characteristics of a body of revolution [PDF]

open access: yes, 1995
The problem of mathematically modelling the symmetric vortex pair formed on the lee side of a body of revolution at moderate incidence to the freestream direction is addressed with a view to predicting its aerodynamic characteristics.
Smith, Howard
core  

The influence of aerodynamic coefficients on the elements of classic projectile paths

open access: yesVojnotehnički Glasnik, 2011
The article deals with the results of the research on the influence of aerodynamic coefficient values on the trajectory elements and the stability parameters of classic axisymmetric projectiles.
Damir D. Jerković, Dušan B. Regodić
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Simulation and Analysis of Aerodynamic Characteristics during Parafoil Canopy Curving Process and Application by LBM

open access: yesAerospace
A parafoil is a crucial aerodynamic deceleration device used in the field of airdrop. The overall objective of this paper is to study the aerodynamic characteristics of the curving process of the canopy using the lattice Boltzmann method, to verify it ...
Yi Wang, Chunxin Yang
doaj   +1 more source

Simulation on Powered Effects of BWB at Take-off Condition

open access: yesXibei Gongye Daxue Xuebao, 2020
The influence of engine powered effects on aerodynamic characteristics of BWB300, which was designed by the Airplane Concept Design Institute of Northwestern Polytechnical University, at take-off condition was analyzed by using the numerical simulation ...

doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

PrandtlPlane High–Lift System Preliminary Aerodynamic Design

open access: yes, 2006
An analysis of low-speed aerodynamics for an unconventional aircraft configuration has been carried out. This configuration, named Prandtlplane, implements Prandtl's Best Wing System for low induced drag.
Iezzi, Giuseppe
core  

Some experimental and theoretical studies in aircraft stability at high angles of attack [PDF]

open access: yes, 1983
A review of techniques for stability and response investigations is presented and the averaging technique of Beecham- Titchener-Simpson is applied to the lateral equations of. motion for two combat aircraft.
Thorne, R.
core  

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