Results 81 to 90 of about 157,884 (362)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Measured and calculated steady aerodynamic loads on a large-scale upper-surface blown model [PDF]
Static aerodynamic loads measurements from wind tunnel tests of a full-scale upper surface blown jet flap configuration are presented. The measured loads are compared with calculations using a method for predicting longitudinal aerodynamic ...
Mendenhall, M. R., Perry, B., III
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Curved centerline air intake for a gas turbine engine [PDF]
, 1980 An inlet for a gas turbine engine was disposed about a curved centerline for the purpose of accepting intake air that is flowing at an angle to engine centerline and progressively turning that intake airflow along a curved path into alignment with the ...
Ruehr, W. C. +2 more
core +1 more source
Study of a Flexible UAV Proprotor [PDF]
, 2013 This paper is concerned with the evaluation of design techniques, both for the propulsive performance and for the structural behavior of a composite flexible proprotor.
Bénard, Emmanuel +5 more
core +2 more sources
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Effects of wing trailing-edge truncation on aerodynamic characteristics of a NASA supercritical-wing research airplane model [PDF]
The Langley 8-foot transonic pressure tunnel was used at Mach numbers from 0.80 to 1.00 to determine the effects of wing trailing-edge truncation on the aerodynamic characteristics of a 0.0625-scale model of a NASA TF-8A supercritical-wing research ...
Bartlett, D. W., Harris, C. D.
core +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Assessment of aerodynamic performance of V/STOL and STOVL fighter aircraft [PDF]
The aerodynamic performance of V/STOL and STOVL fighter/attack aircraft was assessed. Aerodynamic and propulsion/airframe integration activities are described and small and large scale research programs are considered. Uncertainties affecting aerodynamic
Nelms, W. P.
core +1 more source
Aerodynamics and Characteristics of a Spinner Anemometer
Journal of Physics: Conference Series, 2007 A spinner anemometer is a wind measurement concept in which measurements of wind speed in the flow over a wind turbine spinner is used for determination of the free wind. Analogies to the concept are the flow around a sphere and a five hole pitot-tube.
T F Pedersen +2 more
openaire +1 more source