Results 181 to 190 of about 4,272 (296)

Multiscale Architecture and Mechanics of the Cell Nucleus: Implications for Disease, Bioengineering and Nanomedicine

Advanced Science, EarlyView.
Nuclear mechanical properties are inherently scale‐dependent, arising from a hierarchical architecture that spans DNA, chromatin, the nuclear envelope, and condensates. Experimental techniques and theoretical models are integrated into a cohesive multiscale framework linking nanoscale structural features to organelle‐level mechanical behavior.
Xinran Liu, Xin Chen, Qingyang Zhao, Weikang Tan, Lingrui Zhu, Kin Liao, Vincent Chan, Nicolae Goga, Winfred O. Larkotey, Yang Li, Yinghui Shi, Wenya Shu, Lin Wang, Weiqing Wang, Tian Jian Lu, Yulong Han   +15 more
wiley   +1 more source

Residual-learning-enhanced extended Kalman filter for real-time swing angle estimation in quadrotor-suspended-payload systems. [PDF]

Sci Rep
Zhang Y, Shen J, Qiu H, Sha M.
europepmc   +1 more source

Integrated Single‐Cell and Spatial Analysis Reveals a Metabolic‐Immune Axis Driving Aortic Dissection

Advanced Science, EarlyView.
Single‐cell and spatial profiling of 110 human thoracic aortic samples reveals a stromal–immune circuit driving aortic dissection. An elastin‐rich fibroblast subset is depleted with age and markedly reduced in disease, weakening aortic wall integrity.
Jing Tao, Huanjie Yang, Jiahui Yong, Xueting Chen, Qiang Zhao, Xueli Wu, Lei Yan, Li Pang, Fan Luo, Mengjun Yu, Shanshan Pan, Deyang Li, Rouxi Chen, Juan Wang, Zhensheng Dong, Fan Yang, Yue Wang, Yang Chen, Hongjian Zheng, Zhimin Yang, Zijie Wang, Karsten Kristiansen, Hui Peng, Xiaodong Fang, Juan Shen, Yining Yang   +25 more
wiley   +1 more source

Thermoelastic wave propagation in fibre-reinforced plates with exponential temperature-dependent conductivity under fluid-structure interaction. [PDF]

Sci Rep
Almoneef A, Alotaibi M, El-Sapa S, Lotfy K, El-Bary AA.   +4 more
europepmc   +1 more source

Microsphere‐Modulated Sensing‐in‐Energy Supercapacitor With Self‐Filtering Ultra‐Large Signal Under High‐g Shocks

Advanced Science, EarlyView.
To overcome severe signal oscillation under extreme impact conditions, this work presents a Sensing‐in‐Energy microdevice which integrates a MEMS inertial structure directly within a supercapacitor electrolyte cavity. Utilizing shock‐driven transient contact and electrolyte damping for signal self‐filtering, it achieves weak‐oscillation, large ...
Zhihao Zheng, Yiqun Wang, Kaiyou Liu, Shancheng Luan, Yajiang Yin, Xiaofeng Wang, Keren Dai, Zheng You   +7 more
wiley   +1 more source

A high-performance passive galloping-driven dielectric elastomer generator for micro-wind energy harvesting. [PDF]

iScience
Tan J, Zhang J, Zheng S, Du X, Di K, Shen Z, Cai J, Xu Z, E S.   +8 more
europepmc   +1 more source

CD44‐Targeting Hydroxyapatite Nanoparticles (HAP) Induce Mitochondrial Dysfunction‐Driven PANoptosis and Immunogenic Cell Death (ICD) via Ca Overload in Colorectal Cancer

Advanced Science, EarlyView.
ABSTRACT Colorectal cancer (CRC) remains therapeutically challenging due to high metastasis, recurrence, and immunotherapy resistance driven by tumor microenvironment‐mediated immune evasion. Immunogenic cell death (ICD) offers a promising strategy to reshape the immune microenvironment, yet existing ICD inducers suffer from poor targeting efficiency ...
Yao Xiao, Yuxuan Yang, Haosen Qiu, Jia Yang, Hao Liang, Zhaojun Jiang, Xiao Tong, Yongying Li, Qunfeng Huang, Jiaming Wu, Tian Lin, Jiang Yu, Min Liang   +12 more
wiley   +1 more source

Enhanced power capture for the wind turbine system via a novel second-order nonsingular fast terminal sliding mode control strategy. [PDF]

Sci Rep
Shalbafian A, Amiri F.
europepmc   +1 more source

CK2α Deficiency Drives Myocardial Fibrosis via Desmin‐Induced Mitochondrial Dysfunction

Advanced Science, EarlyView.
CK2α preserves mitochondrial homeostasis by phosphorylating Desmin to recruit Cryab, ensuring proper filament assembly. CK2α deficiency disrupts this interaction, causing mitochondrial dysfunction, metabolic shifts, bioenergetic failure, and oxidative stress—ultimately establishing a pro‐fibrotic environment that drives cardiac fibrosis.
Canjie Ma, Jiali Jia, Juncong Lan, Jing Wang, Dan Rao, Lanlan Rao, Weibin Zhang, Dongpeng Wu, Jie Zhang, Gang Wang, Baohua Liu, Ying Ao, Zimei Wang   +12 more
wiley   +1 more source

Aerodynamic Instability Mechanisms of Iced Eight-Bundled Conductors: Frequency-Domain Analysis and Stability Assessment via Wind Tunnel-CFD Synergy. [PDF]

Sensors (Basel)
Zhong B, Qiao M, Cai M, Hu M.
europepmc   +1 more source