A Catalytic Osmium Redox Couple Collapses Cancer Redox Balance
A stable Os(III)/Os(IV) redox couple is developed to disrupt the tumor cell redox balance by concurrently catalyzing ROS generation and GSH depletion. Osmium‐treated cells exhibit multiple cell death pathways, including apoptosis, ferroptosis, and immunogenic cell death.
Wan‐Qiong Huang +9 more
wiley +1 more source
A Review of Pavement Damping Characteristics for Mitigating Tire-Pavement Noise: Material Composition and Underlying Mechanisms. [PDF]
Liu M, Duan W, Dong R, Al-Ammari M.
europepmc +1 more source
This study integrates two complementary traditional Chinese medicine components as precursors to synthesize bioactive AM‐AS@CDs. Compared with single‐component CDs, these dual‐component CDs exhibit enhanced antioxidant capacity and superior renoprotective effects.
Bixiao Liu +10 more
wiley +1 more source
Neural Networks for Estimating Attitude, Line of Sight, and GNSS Ambiguity Through Onboard Sensor Fusion. [PDF]
de Celis R, Cadarso L.
europepmc +1 more source
An endoplasmic reticulum (ER)‐targeted chemodynamic nanoagent (TCBQ/iLD‐ER NPs) comprising •OH‐generating tetrachloro‐1,4‐benzoquinone (TCBQ) and lipid droplets (LDs) formation inhibitor (iLD) is developed for chemodynamic immunotherapy of tumors. After ingestion by cancer cells, TCBQ/iLD‐ER NPs preferentially accumulate in the ER and react with ER ...
Huilan Cai +12 more
wiley +1 more source
Wing hinge dynamics influence stroke amplitudes in flapping wing insects: a frequency response approach. [PDF]
Casey CB +3 more
europepmc +1 more source
ABSTRACT Lung adenocarcinoma (LUAD) remains a leading cause of cancer mortality with limited therapeutic options. Disulfidptosis, a novel cell death modality driven by disulfide stress, represents a promising target, yet its regulation in LUAD is poorly defined. Here, we identify Pannexin 2 (PANX2) as a tumor suppressor in LUAD.
Yi Chen +7 more
wiley +1 more source
Research on the dynamic characteristics of a wind turbine drivetrain based on different control strategies for the generator-side inverter. [PDF]
Zhang S +5 more
europepmc +1 more source
Supramolecular Assembly of Stepped‐Persistent ROS Nanogenerator for Sustained Tumor Immunotherapy
ROS catalytic systems often fail to achieve both effective tumor elimination and persistent immune activation due to their monotonous ROS production profiles. A stepped‐persistent ROS nanogenerator was developed by supramolecularly assembling multiple ROS generation modules within a nanofiber structure to simultaneously extend ROS generation duration ...
Zhenqiang Wang +10 more
wiley +1 more source
An aeroelastic wind energy harvester with continuous orbiting motion and no friction components. [PDF]
Denissenko P, Tucker Harvey S.
europepmc +1 more source

