Results 141 to 150 of about 46,505 (316)

Optimization and Generation in Aerodynamics Inverse Design

CoRR
Inverse design with physics-based objectives is challenging because it couples high-dimensional geometry with expensive simulations, as exemplified by aerodynamic shape optimization for drag reduction. We revisit inverse design through two canonical solutions, the optimal design point and the optimal design distribution, and relate them to optimization
Huaguan Chen, Ning Lin, Luxi Chen, Rui Zhang 0052, Wenbing Huang 0001, Chongxuan Li, Hao Sun 0002   +6 more
openaire   +2 more sources

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

A Mathematical Model to Analyze the Static Stability of Hybrid (Aero- Hydrodynamically Supported) Vehicles. [PDF]

, 2008
Among the new concepts developed for high speed marine vehicles over the last two decades, the "aerodynamic alleviation" approach consists in using an aerodynamic surface to "alleviate" the weight sustained by the hydrodynamic lift.
Patel, Minoo H., Trarieux, Florent, Collu, Maurizio   +2 more
core  

Research progress on aerodynamic stealth design technology of aircraft

Hangkong gongcheng jinzhan
Aerodynamic stealth design is a key technology for aircraft to realize efficient combat in high-risk environments，and it has been a hot technology researched by aviation powers for a long time.
ZHAO Ke, GAO Zhenghong, ZHOU Lin, XIA Lu, DENG Jun, HUANG Jiangtao   +5 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Creating aero-databases by adaptive-fidelity CFD coupled with S&C analysis to predict flying qualities

, 2009
CEASIOM, the Computerized Environment for Aircraft Synthesis and Integrated Optimization Methods, is a framework tool that integrates discipline-specific tools for conceptual design.
Tomac, M., Mieszalski, D., Vos, J., Rizzi, A., Goetzendorf-Grabowski, T., Da Ronch, A., Ghoreyshi, M.   +6 more
core  

Study on landing control method based on incremental dynamic inverse

Hangkong gongcheng jinzhan
Accurate landing control and improving the safety and reliability of the landing process are difficult issues in the safe recovery of carrier based aircraft. A landing control system based on incremental dynamic inverse is proposed.
DUAN Zhuoyi, ZHAO Letian, ZHANG Junhong, LIU Xiaoxiong   +3 more
doaj   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

CFD-based shape optimisation with grid-enabled design search toolkits

, 2003
This paper presents an application of applying Grid computing technologies in the field of engineering design optimisation using computational fluid dynamics (CFD).
Keane, Andy, Cox, Simon, Song, Wenbin
core