Results 131 to 140 of about 163,941 (314)

Design of 3-dimensional complex airplane configurations with specified pressure distribution via optimization [PDF]

open access: yes
A subcritical panel method applied to flow analysis and aerodynamic design of complex aircraft configurations is presented. The analysis method is based on linearized, compressible, subsonic flow equations and indirect Dirichlet boundary conditions ...
Kubrynski, Krzysztof
core   +1 more source

High-speed-propeller wind-tunnel aeroacoustic results [PDF]

open access: yes, 1980
Some aerodynamic concepts are presented together with an explanation of how these concepts are applied to advanced propeller design. The unique features of this propulsion system are addressed with emphasis on the design concepts being considered for the
Dittmar, J. H., Jeracki, R. J.
core   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Airfoil Design Optimization of Blended Wing Body for Various Aerodynamic and Stealth Stations

open access: yesAerospace
The airfoil is the foundation of an aircraft, and its characteristics have a significant impact on those of the aircraft. Conventional airfoil design mainly focuses on improving aerodynamic performance, while flying wing airfoil designs should also ...
Wei Zhang   +5 more
doaj   +1 more source

Optimization and design of three-dimensional aerodynamic configurations of arbitrary shape by a vortex lattice method [PDF]

open access: yes
A new method based on vortex lattice theory has been developed which can be applied to the combined analysis, induced drag optimization, and aerodynamic design of three-dimensional configurations of arbitrary shape.
Feifel, W. M.
core   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

open access: yesFEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim   +11 more
wiley   +1 more source

A Tension Shell Structure for Application to Entry Vehicles [PDF]

open access: yes
The shape of a shell of revolution designed t o have only tensile stresses under axisymmetric aerodynamic loadings has been derived on the basis of linear membrane theory. values of circumferential tension is also given.
Anderson, Melvin S.   +3 more
core   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Computational fluid dynamics applications at McDonnel Douglas [PDF]

open access: yes
Representative examples are presented of applications and development of advanced Computational Fluid Dynamics (CFD) codes for aerodynamic design at the McDonnell Douglas Corporation (MDC).
Hakkinen, R. J.
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

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