Results 61 to 70 of about 12,489,898 (339)

DELP Treatment on Vision and Retinal Microcirculation in Patients With Acute Ischemic Stroke: Report of Five Cases and Literature Review

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background The delipid extracorporeal lipoprotein filter from plasma (DELP) treatment can effectively reduce blood lipid, increase blood flow, and improve neurological deficits in patients with acute ischemic stroke (AIS). However, its effect on vision and retinal microcirculation in stroke patients has never been reported.
Ning Li   +9 more
wiley   +1 more source

Aerodynamic Intelligent Topology Design (AITD)-A Future Technology for Exploring the New Concept Configuration of Aircraft

open access: yesAerospace, 2023
With the increasing requirements for aerodynamic performance, aerodynamic configuration design of aircraft based on traditional design experience has gradually failed to meet the needs of the future.
Peng Liao   +4 more
doaj   +1 more source

Airplane wing leading edge variable camber flap [PDF]

open access: yes, 1980
The invention and design of an aerodynamic high lift device which provided a solution to an aircraft performance problem are described. The performance problem of converting a high speed cruise airfoil into a low speed aerodynamic shape that would ...
Cole, J. B.
core   +1 more source

Aerodynamic Design of Nozzles with Uniform Outflow for Hypervelocity Ground-Test Facilities

open access: yesJournal of Propulsion and Power, 2018
A method is proposed for the aerodynamic design of nozzles with uniform outflow for supersonic and hypersonic ground-test facilities.
W. Chan   +5 more
semanticscholar   +1 more source

A Comparative Study of Cerebral Oxygenation During Exercise in Hemodialysis and Peritoneal Dialysis Patients

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Cognitive impairment and exercise intolerance are common in dialysis patients. Cerebral perfusion and oxygenation play a major role in both cognitive function and exercise execution; HD session per se aggravates cerebral ischemia in this population. This study aimed to compare cerebral oxygenation and perfusion at rest and in mild
Marieta P. Theodorakopoulou   +10 more
wiley   +1 more source

Separable shape tensors for aerodynamic design

open access: yesJournal of Computational Design and Engineering, 2023
AbstractAirfoil shape design is a classical problem in engineering and manufacturing. In this work, we combine principled physics-based considerations for the shape design problem with modern computational techniques using a data-driven approach. Modern and traditional analyses of two-dimensional (2D) and three-dimensional (3D) aerodynamic shapes ...
Zachary J Grey   +2 more
openaire   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Research on the influence of deicing airbag and simplified model on aerodynamic characteristics

open access: yesHangkong gongcheng jinzhan
As a common deicing system for turboprop aircraft,it is of great significance to evaluate the influence of deicing airbag on the aerodynamic characteristics of the aircraft. Based on the aerodynamic deicing system installed on one aircraft,simulating the
CHEN Lu, MA Yumin, LI Yan
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

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