Results 21 to 30 of about 5,970 (262)

Optimization of Temperature Measurement Method for High-Pressure Gas Flow Standard Facility Based on Sonic Nozzle Array

Aerospace
To improve the accuracy of the wind tunnel test, relying on the high-pressure gas source of the China Aerodynamic Research and Development Center, a secondary flow standard facility based on a sonic nozzle array was developed, with a pressure range of (1~
Zhihao Zhang, Jiaxi Zhao, Tingting Liu, Rongping Zhang   +3 more
doaj   +1 more source

Estimation methods for aerodynamic noise generated from the bogie section of Shinkansen trains by using wind tunnel test

Nihon Kikai Gakkai ronbunshu, 2017
A method has been developed for predicting the aerodynamic noise from the bogie of a high-speed train using a two-dimensional microphone array in a low-noise wind tunnel.
Nobuhiro YAMAZAKI, Toshiki KITAGAWA, Toki UDA, Takeshi KURITA, Yusuke WAKABAYASHI, Takanobu NISHIURA   +5 more
doaj   +1 more source

Experimental Investigation of Airfoil Instability Tonal Noise Reduction Using Structured Porous Trailing Edges

Applied Sciences
Reducing the tonal noise from airfoil instabilities has attracted significant interest from the aeronautical community in the past few years. The aim of this paper is to investigate the effect of structured porous trailing edges on the tonal noise ...
Yong Wang, Kongcheng Zuo, Peng Guo, Kun Zhao, Victor Feliksovich Kopiev   +4 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Research on intelligent diagnosis of deep-sea submersible bearing failures based on dual adaptive modeling [PDF]

AIP Advances
The deep-sea environment is extremely complex, and rolling bearings in submersible propulsion systems are the core moving components. Facing complex conditions and multiple faults, traditional bearing fault diagnosis methods lack adaptability—failing to ...
Kunbo Xu, Dongjun Liu, Zekai Zong, Chaoge Wang, Ran Wang, Funa Zhou, Xiong Hu   +6 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Flow structure and unsteady characteristics of fountain flow induced by dual impinging jets

Kongqi donglixue xuebao
The flow-field structure and mechanical characteristics of dual impinging jets are critical issues during the takeoff and landing phases of aircraft. However, the unsteady characteristics of the fountain effect induced by dual impinging jets have not yet
Yifan Zhao, Rongping Zhang, Rongping Zhang, Yuxiang Liang, Yuxiang Liang, Jiaxi Zhao, Jiaxi Zhao, Xunnian Wang   +7 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source