Results 31 to 40 of about 1,147,066 (240)

Identification and attenuation of slat noise [PDF]

open access: yes, 2012
In the case of civil transport aircraft, engines were the dominant noise source until the advent of the high-bypass ratio engines in the early 1970s. Since then, airframe noise has become more important, particularly during the approach-to-landing stage ...
Chen, Peng
core   +1 more source

Experimental Investigation of Airfoil Instability Tonal Noise Reduction Using Structured Porous Trailing Edges

open access: yesApplied Sciences
Reducing the tonal noise from airfoil instabilities has attracted significant interest from the aeronautical community in the past few years. The aim of this paper is to investigate the effect of structured porous trailing edges on the tonal noise ...
Yong Wang   +4 more
doaj   +1 more source

Estimation methods for aerodynamic noise generated from the bogie section of Shinkansen trains by using wind tunnel test

open access: yesNihon Kikai Gakkai ronbunshu, 2017
A method has been developed for predicting the aerodynamic noise from the bogie of a high-speed train using a two-dimensional microphone array in a low-noise wind tunnel.
Nobuhiro YAMAZAKI   +5 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Flow structure and unsteady characteristics of fountain flow induced by dual impinging jets

open access: yesKongqi donglixue xuebao
The flow-field structure and mechanical characteristics of dual impinging jets are critical issues during the takeoff and landing phases of aircraft. However, the unsteady characteristics of the fountain effect induced by dual impinging jets have not yet
Yifan Zhao   +7 more
doaj   +1 more source

The Application of a Linear Microphone Array in the Quantitative Evaluation of the Blade Trailing-Edge Noise Reduction

open access: yesApplied Sciences, 2021
This paper concerns the application of a linear microphone array in the quantitative evaluation of blade trailing-edge (TE) noise reduction. The noise radiation from the blades with straight and serrated TEs is measured in an indoor open-jet wind tunnel.
Weijie Chen   +4 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

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