Results 31 to 40 of about 11,859 (310)

The effect of wavy leading edges on aerofoil-gust interaction noise [PDF]

, 2013
High-order accurate numerical simulations are performed to investigate the effects of wavy leading edges (WLEs) on aerofoil–gust interaction (AGI) noise.
Lau, A.S.H., Kim, J.W., Haeri, S.
core   +1 more source

Experimental Investigation of Airfoil Instability Tonal Noise Reduction Using Structured Porous Trailing Edges

Applied Sciences
Reducing the tonal noise from airfoil instabilities has attracted significant interest from the aeronautical community in the past few years. The aim of this paper is to investigate the effect of structured porous trailing edges on the tonal noise ...
Yong Wang, Kongcheng Zuo, Peng Guo, Kun Zhao, Victor Feliksovich Kopiev   +4 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Research on intelligent diagnosis of deep-sea submersible bearing failures based on dual adaptive modeling [PDF]

AIP Advances
The deep-sea environment is extremely complex, and rolling bearings in submersible propulsion systems are the core moving components. Facing complex conditions and multiple faults, traditional bearing fault diagnosis methods lack adaptability—failing to ...
Kunbo Xu, Dongjun Liu, Zekai Zong, Chaoge Wang, Ran Wang, Funa Zhou, Xiong Hu   +6 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Flow structure and unsteady characteristics of fountain flow induced by dual impinging jets

Kongqi donglixue xuebao
The flow-field structure and mechanical characteristics of dual impinging jets are critical issues during the takeoff and landing phases of aircraft. However, the unsteady characteristics of the fountain effect induced by dual impinging jets have not yet
Yifan Zhao, Rongping Zhang, Rongping Zhang, Yuxiang Liang, Yuxiang Liang, Jiaxi Zhao, Jiaxi Zhao, Xunnian Wang   +7 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Relationship between Separated Vortex around NACA blade and Aerodynamic Noise [PDF]

, 2009
To clarify the mechanism of the aerodynamic noise generated by the separated vortex around a NACA blade is aimed. The relation between the angle of attack and the aerodynamic noise of the blade are analyzed by the wind tunnel experiment and a commercial ...
佐々木, 壮一, 高松, 肇一, 林, 秀千人   +2 more
core  

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source