Results 101 to 110 of about 68,481 (311)

Advances in Aerodynamic Shape Optimization [PDF]

open access: yes, 2005
The accumulated experience of the last decade suggests that most existing aircraft which cruise at transonic speeds are amenable to a drag reduction of the order of 3 to 5 percent, or an increase in the drag rise Mach number of at least .02. These improvements can be achieved by very small shape modifications, which are too subtle to allow their ...
openaire   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Optimization of projectile aerodynamic parameters based on hybrid genetic algorithm

open access: yesJournal of Measurement Science and Instrumentation, 2015
Aerodynamic parameters are important factors that affect projectile flight movement.To obtain accurate aerodynamic parameters,a hybrid genetic algorithm is proposed to identify and optimize the aerodynamic parameters of projectile.By combining the ...
LIU Lin   +4 more
doaj  

Propeller Aerodynamic Design and Optimization

open access: yes, 2023
This research endeavors to illuminate the path toward efficient and optimized propeller design by delving into the realm of aerodynamics. Propellers, as vital mechanical marvels, constitute the core of numerous propulsion systems, spanning from aircraft and marine vessels to wind turbines.
openaire   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

open access: yesAging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef   +2 more
wiley   +1 more source

Cognitive Status in People With Epilepsy in the Republic of Guinea: A Prospective, Case–Control Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with epilepsy (PWE) may experience cognitive deficits but fail to undergo formal evaluation. This study compares cognitive status between PWE and healthy controls in the West African Republic of Guinea. Methods A cross‐sectional, case–control study was conducted in sequential recruitment phases (July 2024–July 2025) at Ignace ...
Maya L. Mastick   +14 more
wiley   +1 more source

Integrated aerodynamic/dynamic optimization of helicopter rotor blades [PDF]

open access: yes
An integrated aerodynamic/dynamic optimization procedure is used to minimize blade weight and 4 per rev vertical hub shear for a rotor blade in forward flight.
Chattopadhyay, Aditi   +2 more
core   +1 more source

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin   +11 more
wiley   +1 more source

Rapid Aerodynamic Shape Optimization With Payload Size Constraints for Hypersonic Vehicle

open access: yesIEEE Access, 2019
Nowadays, aerodynamic shape optimization of the hypersonic vehicle is mostly optimized for local details such as the wing. In the overall shape optimization, the conceptual design of the vehicle is more common, in which the shape is described in fewer ...
Wuyu Peng, Zhiwei Feng, Tao Yang
doaj   +1 more source

Transonic transport study: Structures and aerodynamics [PDF]

open access: yes
The structural and aerodynamic aspects of a general study of advanced transonic transports are presented. Aircraft designed to cruise at Mach numbers of 0.90, 0.98, and 1.15 were comparatively analyzed.
Ardema, M. D., Williams, L. J.
core   +1 more source

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