Results 41 to 50 of about 67,904 (291)
Discrete Adjoint-Based Simultaneous Analysis and Design Approach for Conceptual Aerodynamic Optimization [PDF]
INCAS Bulletin, 2017 In this paper, a simultaneous analysis and design method is derived and applied for a non-linear constrained aerodynamic optimization problem. The method is based on the approach of defining a Lagrange functional based on the objective function and the ...
Oliviu SUGAR-GABOR
doaj +1 more source
Atmosphere, 2022 Corner modifications can reduce wind loads acting on supertall buildings and modify the corresponding flow structures. The present study investigated the aerodynamic shape optimization of the corner recession square cylinders with multiple geometric ...
Zhaoyong Wang +3 more
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A multifidelity multiobjective optimization framework for high-lift airfoils [PDF]
, 2016 High-lift devices design is a challenging task as it involves highly complex flow features while being critical for the overall performance of the aircraft.
Demange, Jean +2 more
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Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Wing Design and Adaptive Optimization of a Compound Drone
气体物理With the growing demand for unmanned transportation, the rise of compound drones is imperative. Aerodynamic optimization design plays a significant role in the development cycle of compound drones.
Wei ZHANG +4 more
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Efficient preliminary floating offshore wind turbine design and testing methodologies and application to a concrete spar design [PDF]
, 2015 The current key challenge in the floating offshore wind turbine industry and research is on designing economic floating systems that can compete with fixed-bottom offshore turbines in terms of levelized cost of energy. The preliminary platform design, as
Campos Hortigüela, Alexis +4 more
core +2 more sources
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Cluster-based feedback control of turbulent post-stall separated flows
, 2018 We propose a novel model-free self-learning cluster-based control strategy for general nonlinear feedback flow control technique, benchmarked for high-fidelity simulations of post-stall separated flows over an airfoil. The present approach partitions the
Brunton, Steven L. +5 more
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Tiltrotor CFD part II: aerodynamic optimisation of tiltrotor blades [PDF]
, 2017 This paper presents aerodynamic optimisation of tiltrotor blades with high-fidelity computational fluid dynamics. The employed optimisation framework is based on a quasi-Newton method, and the required high-fidelity flow gradients were computed using a
Barakos, G.N. +5 more
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source