Results 51 to 60 of about 15,080 (315)

Aerodynamic Optimization of a Winglet Design [PDF]

EPJ Web of Conferences, 2013
In the present study, an experimental study is presented for a flow around an isolated wing equipped by a winglet and profiled with Naca 0012. Several cases of winglets were tested according to the angle ß: 0°, 55°, 65°and 75°. For all these cases at a velocity of 20, 30 and 40 meters per second, wind tunnel tests are performed and compared for ...
S. Belferhat, Sidi Mohamed Amine Meftah, Tayeb Yahiaoui, Bachir Imine   +3 more
openaire   +2 more sources

Accelerated Airfoil Optimization via a Geometry-Based Discriminator Within Particle Swarm Optimization

IEEE Access
Particle swarm optimization (PSO) is widely used for aerodynamic shape optimization; however, its practical efficiency is often limited by the high computational cost of aerodynamic evaluations and the frequent generation of geometrically unrealistic ...
Leul Walelign Michael, Abdulazez Abagero, Abera Tullu, Yoseph Mekonnen Abebe, Sunghun Jung   +4 more
doaj   +1 more source

Aerodynamic Shape Optimization of a Square Cylinder with Multi-Parameter Corner Recession Modifications

Atmosphere, 2022
Corner modifications can reduce wind loads acting on supertall buildings and modify the corresponding flow structures. The present study investigated the aerodynamic shape optimization of the corner recession square cylinders with multiple geometric ...
Zhaoyong Wang, Chaorong Zheng, Joshua Adriel Mulyanto, Yue Wu   +3 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

An Improved Approach for Reducing the Dimensionality of Wing Aerodynamic Optimization Considering Longitudinal Stability

Aerospace
The wing aerodynamic shape optimization is a typical high-dimensional problem with numerous independent design variables. Researching methods to reduce the dimensionality of optimization from the perspective of aerodynamic characteristics is necessary ...
Boqian Ji, Jun Huang, Xiaoqiang Lu, Yacong Wu, Jingjiang Liu   +4 more
doaj   +1 more source

Research on Efficient Particle Swarm Optimization and Aerodynamic Stealth Integrated Design of Fly-wing UAV

Hangkong gongcheng jinzhan, 2019
To deal with the problem of aerodynamic and stealth integrated optimization of fly-wing UAV, a multi-objective optimization study on aerodynamic and stealth of the fly-wing UAV is carried out which based on the free-form surface deformation(FFD). The FFD
Fan Huayu, Zhan Hao, Cheng Shixin, Mi Baigang, Yao Huiqin   +4 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

GCN-based 3D aerodynamic optimization design based on discrete adjoint method

Kongqi donglixue xuebao
Gradient-based optimization algorithms, particularly the discrete adjoint method, are widely used in aerodynamic shape optimization due to their independence from design variable dimensionality.
Dian Zhao, Jinpeng Xiang, Shufang Song
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Stealth Unmanned Aerial Vehicle Penetration Efficiency Optimization Based on Radar Detection Probability Model

Aerospace
Aerodynamic/stealth optimization is a key issue during the design of a stealth UAV. Balancing the weight of different incident angles of the RCS and combining stealth characteristics with aerodynamic characteristics are hotspots of aerodynamic/stealth ...
Chengen Yuan, Dongli Ma, Yuhong Jia, Liang Zhang   +3 more
doaj   +1 more source