Results 51 to 60 of about 5,838 (267)

Surrogate-based evolutionary optimization of aerodynamic performance and emitted sound for an impeller fan

Engineering Applications of Computational Fluid Mechanics
Centrifugal fans are widely used in building ventilation and air-conditioning systems but face increasing demands for higher energy efficiency, improved performance, and lower noise levels.
Hamid Motamedi Zokae, David Moxey, Gavin Tabor   +2 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Stealth Unmanned Aerial Vehicle Penetration Efficiency Optimization Based on Radar Detection Probability Model

Aerospace
Aerodynamic/stealth optimization is a key issue during the design of a stealth UAV. Balancing the weight of different incident angles of the RCS and combining stealth characteristics with aerodynamic characteristics are hotspots of aerodynamic/stealth ...
Chengen Yuan, Dongli Ma, Yuhong Jia, Liang Zhang   +3 more
doaj   +1 more source

Research on Efficient Particle Swarm Optimization and Aerodynamic Stealth Integrated Design of Fly-wing UAV

Hangkong gongcheng jinzhan, 2019
To deal with the problem of aerodynamic and stealth integrated optimization of fly-wing UAV, a multi-objective optimization study on aerodynamic and stealth of the fly-wing UAV is carried out which based on the free-form surface deformation(FFD). The FFD
Fan Huayu, Zhan Hao, Cheng Shixin, Mi Baigang, Yao Huiqin   +4 more
doaj   +1 more source

Discrete Adjoint-Based Simultaneous Analysis and Design Approach for Conceptual Aerodynamic Optimization [PDF]

INCAS Bulletin, 2017
In this paper, a simultaneous analysis and design method is derived and applied for a non-linear constrained aerodynamic optimization problem. The method is based on the approach of defining a Lagrange functional based on the objective function and the ...
Oliviu SUGAR-GABOR
doaj   +1 more source

Propeller Aerodynamic Design and Optimization

, 2023
This research endeavors to illuminate the path toward efficient and optimized propeller design by delving into the realm of aerodynamics. Propellers, as vital mechanical marvels, constitute the core of numerous propulsion systems, spanning from aircraft and marine vessels to wind turbines.
openaire   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Efficient aerodynamic shape optimization by using unsupervised manifold learning to filter geometric features

Engineering Applications of Computational Fluid Mechanics
Many aerodynamic shape optimization methods often focus on utilizing the end-to-end relationship between design variables and aerodynamic performance to find the optimal design, while overlooking the exploration of geometric knowledge of the shape itself.
Long Ma, Xiao-Jing Wu, Wei-Wei Zhang
doaj   +1 more source

Advances in Aerodynamic Shape Optimization [PDF]

, 2005
The accumulated experience of the last decade suggests that most existing aircraft which cruise at transonic speeds are amenable to a drag reduction of the order of 3 to 5 percent, or an increase in the drag rise Mach number of at least .02. These improvements can be achieved by very small shape modifications, which are too subtle to allow their ...
openaire   +1 more source

Aerodynamic Optimization of a Winglet Design [PDF]

EPJ Web of Conferences, 2013
In the present study, an experimental study is presented for a flow around an isolated wing equipped by a winglet and profiled with Naca 0012. Several cases of winglets were tested according to the angle ß: 0°, 55°, 65°and 75°. For all these cases at a velocity of 20, 30 and 40 meters per second, wind tunnel tests are performed and compared for ...
S. Belferhat, Sidi Mohamed Amine Meftah, Tayeb Yahiaoui, Bachir Imine   +3 more
openaire   +2 more sources