Results 71 to 80 of about 15,080 (315)

Application of Nontraditional Optimization Techniques for Airfoil Shape Optimization

open access: yesModelling and Simulation in Engineering, 2012
The method of optimization algorithms is one of the most important parameters which will strongly influence the fidelity of the solution during an aerodynamic shape optimization problem.
R. Mukesh, K. Lingadurai, U. Selvakumar
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

An optimization procedure of shape and position of the aerodynamic device at the rear side of a semi-trailer truck model

open access: yesHeliyon
The paper outlines the development and optimization of an aerodynamic device for a semi-trailer truck model to reduce aerodynamic drag force. The optimization procedure involves the selection of a basic aerodynamic device shape, using airfoil profiles ...
Stjepan Galamboš   +5 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Aerodynamic Shape Optimization Using the Discrete Adjoint of the Navier-Stokes Equations: Applications Toward Complex 3D Configutations

open access: yes, 2009
Within the next few years, numerical shape optimization based on high fidelity methods is likely to play a strategic role in future aircraft design. In this context, suitable tools have to be developed for solving aerodynamic shape optimization problems,
Dwight, Richard P.   +5 more
core  

Conceptual design and optimization methodology for box wing aircraft [PDF]

open access: yes, 2012
A conceptual design optimization methodology was developed for a medium range box wing aircraft. A baseline conventional cantilever wing aircraft designed for the same mis- sion and payload was also optimized alongside a baseline box wing aircraft.
Jemitola, Paul Olugbeji
core  

Application of Multidisciplinary Design Optimization on Advanced Configuration Aircraft

open access: yesJournal of Aerospace Technology and Management, 2017
An optimization strategy is constructed to solve the aerodynamic and structural optimization problems in the conceptual design of double-swept flying wing aircraft. Aircraft preliminary aerodynamic and structural design optimization is typically based on
Yalin Pan   +3 more
doaj  

Geometry Design Optimization of a Wind Turbine Blade Considering Effects on Aerodynamic Performance by Linearization

open access: yesEnergies, 2020
For a wind turbine to extract as much energy as possible from the wind, blade geometry optimization to maximize the aerodynamic performance is important.
Kyoungboo Yang
doaj   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Aerodynamic design optimization using flow feature parameterization

open access: yes, 2007
Design optimization methods using high-fidelity computational fluid dynamics simulations are becoming increasingly popular in the area of aerodynamic design, sustaining the desire to make these methods more computationally efficient.
Barrett, Thomas Robin
core  

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