Results 81 to 90 of about 68,481 (311)

Aerodynamic design using numerical optimization [PDF]

open access: yes
The procedure of using numerical optimization methods coupled with computational fluid dynamic (CFD) codes for the development of an aerodynamic design is examined.
Chapman, G. T., Murman, E. M.
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Aerodynamic Shape Optimization of Subsonic/Supersonic Flows Integrating Variable-Fidelity Longitudinal Trim Analysis

open access: yesAerospace
Most existing studies on aerodynamic shape optimization have not considered longitudinal trim under control surface deflection, typically achieving self-trim through a constraint of zero pitching moment or adjusting the optimized configuration for ...
Yacong Wu   +3 more
doaj   +1 more source

On simple aerodynamic sensitivity derivatives for use in interdisciplinary optimization [PDF]

open access: yes
Low-aspect-ratio and piston aerodynamic theories are reviewed as to their use in developing aerodynamic sensitivity derivatives for use in multidisciplinary optimization applications.
Doggett, Robert V., Jr.
core   +1 more source

Optimal mistuning for enhanced aeroelastic stability of transonic fans [PDF]

open access: yes, 1983
An inverse design procedure was developed for the design of a mistuned rotor. The design requirements are that the stability margin of the eigenvalues of the aeroelastic system be greater than or equal to some minimum stability margin, and that the mass ...
Crawley, E. F., Hall, K. C.
core   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

Optimization and design of three-dimensional aerodynamic configurations of arbitrary shape by a vortex lattice method [PDF]

open access: yes
A new method based on vortex lattice theory has been developed which can be applied to the combined analysis, induced drag optimization, and aerodynamic design of three-dimensional configurations of arbitrary shape.
Feifel, W. M.
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Validation of a pair of computer codes for estimation and optimization of subsonic aerodynamic performance of simple hinged-flap systems for thin swept wings [PDF]

open access: yes
Extensive correlations of computer code results with experimental data are employed to illustrate the use of linearized theory attached flow methods for the estimation and optimization of the aerodynamic performance of simple hinged flap systems.
Carlson, Harry W., Darden, Christine M.
core   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

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