Results 71 to 80 of about 10,735,463 (237)

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

A novel shape optimization method using knot insertion algorithm in B-spline and its application to transonic airfoil design [PDF]

open access: yes, 2011
A new method using the cubic B-spline curves with nominal uniform knot set to parameterize the geometry is proposed to deal with shape optimization problems.
Xu, B.   +4 more
core   +1 more source

Rapid design method of rocket aerodynamic shape based on conditional diffusion model

open access: yesKongqi donglixue xuebao
Aerodynamic design plays a vital role in rocket design. To expedite the design process of rocket aerodynamic shapes and minimize tedious iterative optimization, this study proposes a generative rapid inverse design method for rocket aerodynamic shapes ...
Chuan Li   +5 more
doaj   +1 more source

Aerodynamic Optimization of a Winglet Design

open access: yesEPJ Web of Conferences, 2013
In the present study, an experimental study is presented for a flow around an isolated wing equipped by a winglet and profiled with Naca 0012. Several cases of winglets were tested according to the angle ß: 0°, 55°, 65°and 75°.
Yahiaoui T.   +3 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Comparison between Gradient-free and Adjoint Based Aerodynamic Optimization of a Flying Wing Transport Aircraft in the Preliminary Design. [PDF]

open access: yes, 2007
This paper describes investigations of planform and shape optimizations for a flying wing transport aircraft with an Euler continuous adjoint method.
Arno, Ronzheimer   +2 more
core  

Optimization techniques with knowledge based control in ship concept design [PDF]

open access: yes, 1990
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.An integrated computational approach to Ship Concept Design using optimization techniques and a knowledge base to control the optimization process has been ...
Schachter, Richard David
core   +4 more sources

Preface to the column on "Aircraft Multidisciplinary Optimization Design Technology Based on Adjoint Theory"

open access: yesKongqi donglixue xuebao
The aerodynamic configuration of an aircraft determines its shape and directly influences flight performance, platform functionality, and mission effectiveness. In modern aircraft development, increasing performance demands and technical complexity cause
Zhenghong Gao, Chengjun He, Lin Zhou
doaj   +1 more source

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