Results 51 to 60 of about 3,498,285 (189)

Robust aerodynamic design of variable speed wind turbine rotors [PDF]

open access: yes, 2012
This study focuses on the robust aerodynamic design of the bladed rotor of small horizontal axis wind turbines. The optimization process also considers the effects of manufacturing and assembly tolerances on the yearly energy production.
Vasile, Massimiliano   +2 more
core   +3 more sources

Integrated Design Optimization of Aerodynamic Shape and Flow Control Parameters for Co-Flow Jet Airfoils

open access: yesAerospace
Co-Flow Jet (CFJ) technology is an effective active flow control method for improving aerodynamic performance by enhancing circulation and suppressing flow separation.
Keying Chen   +4 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Optimization using surrogate models and partially converged computational fluid dynamics simulations [PDF]

open access: yes, 2006
Efficient methods for global aerodynamic optimization using computational fluid dynamics simulations should aim to reduce both the time taken to evaluate design concepts and the number of evaluations needed for optimization.
Alexander I.J. Forrester   +5 more
core   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Aerodynamic Design and Shape Optimization with the Far-Field Drag Decomposition Approach

open access: yesXibei Gongye Daxue Xuebao, 2020
In the aerodynamic shape design, the drag prediction has always been an extremely challenging mission for the exploration of a configuration. As for the more complex configurations, it is especially desired to the availability of a highly accurate and ...

doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Comparison between Gradient-free and Adjoint Based Aerodynamic Optimization of a Flying Wing Transport Aircraft in the Preliminary Design. [PDF]

open access: yes, 2007
This paper describes investigations of planform and shape optimizations for a flying wing transport aircraft with an Euler continuous adjoint method.
Arno, Ronzheimer   +2 more
core  

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