Results 51 to 60 of about 121,945 (278)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Advances in Aerodynamics, 2020 The DSMC modeling is developed to simulate three-dimensional (3D) rarefied ionization flows and numerically forecast the communication blackout around spacecraft during hypervelocity reentry.
Ming Fang +4 more
doaj +1 more source
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
AerospaceTo clarify the influence of the serpentine nozzle configurations on the flow characteristics and aerodynamic performance of aircraft, the flow features and aerodynamic performances of the double-ducted serpentine nozzles with different aspect ratios (AR),
Jilong Zhu +6 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Nanjing Hangkong Hangtian Daxue XuebaoSince child aircraft are significantly impacted by the wake interference from the mother aircraft during aerial refueling or the autonomous recovery of unmanned aerial vehicles（UAVs）， a rapid prediction model for dual‑aircraft aerodynamic interference is
YUE Hao +4 more
doaj +1 more source
Integration of ejectors into high-speed aircraft [PDF]
, 1979 The integration of ejectors into forebodies is considered for transonic and supersonic flight.
Duvvuri, T.
core +1 more source
A computational assessment of the aerodynamic performance of a tilted Darrieus wind turbine [PDF]
, 2015 The aerodynamic performance of a Darrieus wind turbine operating with the rotation axis tilted with respect to the free-stream wind speed is investigated in this paper. An Unsteady Reynolds Averaged Navier Stokes (URANS) Computational Fluid Dynamics (CFD)
Bedon, Gabriele +2 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Applied SciencesAdjoint-based mesh adaptation method serves as an effective approach to improve the predictive accuracy of aerodynamic characteristics. However, viscous boundary layer grids often encounter issues such as hanging nodes, negative volumes, and directional ...
Pengcheng Cui +8 more
doaj +1 more source