Results 81 to 90 of about 2,332 (298)

CFD Investigation of the Effect of the Salient Flow Features in the Wake of a Generic Open-Wheel Race Car [PDF]

, 2015
It is well known that in motorsport the wake from an upstream vehicle can be detrimental to the handling characteristics of a following vehicle, in particular in formulae with high levels of downforce.
Newbon, Joshua, Dominy, Robert, Sims-Williams, David   +2 more
core   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Aerodynamic Optimization of Box Wing – A Case Study

International Journal of Aviation, Aeronautics, and Aerospace, 2014
The optimization of a possible medium range box wing commercial airliner is presented in three stages. Preliminary research is used to determine various parameters for a potential box wing model, and a baseline model is designed in Autodesk Inventor ...
Adeel Khalid, Parth Kumar
doaj   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Investigating cell viability under shear stress in complex microstreaming flows generated by ultrasound-driven actuated microbubbles

Flow
In this study, we introduce a method, applied for the first time to manipulate human cells, by leveraging the controlled activation and deactivation of microbubble streaming – previously used for rigid polymer particles. This innovative technique enables
Amirabas Bakhtiari, Benedikt Schumm, Martin Schönfelder, Christian J. Kähler   +3 more
doaj   +1 more source

A New Method for the Prediction of the Downwash Angle Gradient

International Journal of Aviation, Aeronautics, and Aerospace, 2019
A new method for the prediction of the downwash angle gradient due to aircraft wings across the span of an aft horizontal tail in the incompressible regime is presented.
MONDHER YAHYAOUI
doaj   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Base Pressure Control using Micro-jets in Supersonic Flow Regimes

International Journal of Aviation, Aeronautics, and Aerospace, 2018
Base pressure plays a vital role in aerospace-related applications and its control is essential in reduction of drag and improving fuel consumption. Low pressure at the base of Rockets, Missiles, bombs and shells are a very common problem happening at ...
Vigneshvaran Sethuraman, Sher Afghan Khan   +1 more
doaj   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Wingtip Vortex Alleviation Using a Reverse Delta Type Add-on Device

International Journal of Aviation, Aeronautics, and Aerospace, 2017
The result of interactions of a wingtip vortex of a half-span wing and vortices generated by a slender reverse delta type add-on device were studied using Particle Image Velocimetry in a closed-loop low-speed wind tunnel.
Afaq Altaf
doaj   +1 more source