Spatiotemporal Regulation of Hierarchical Assembly of Hydroxyapatite for Enamel Remineralization
Biomimetic repair exhibits unique advantages for enamel regeneration compared with conventional clinical treatments. An enzymatic mineralization system (EMS) is developed, where the resulting HAP nanorods hierarchically assemble into a highly ordered structure on the enamel surface through the spatiotemporal modulation of interfacial energies of ...
Zhenhang Tang +15 more
wiley +1 more source
Amended engineered soil promotes coordinated soil-plant-microbiome responses during early-stage slope restoration. [PDF]
Chen Z +6 more
europepmc +1 more source
LigHTS: Biomimetic Hydrogel Photo‐Fabrication for Imaging‐Based Ultra‐High‐Throughput Screening
LigHTS removes a key bottleneck for ultra‐high‐throughput screening (UHTS) by enabling biomimetic hydrogel microenvironments to be manufactured directly in standard multiwell plates. A single, collimated UV exposure with formulation‐tuned light penetration patterns an entire plate with UHTS‐grade uniformity (<20% CV), producing structured GelMA films ...
Alessandro Enrico +7 more
wiley +1 more source
Factors Predicting the Outcome in Patients With Acute Encephalitis Syndrome: A Retrospective Analysis of Surveillance Data in Bangladesh. [PDF]
Rahman DI +23 more
europepmc +1 more source
Chiral virus‐mimicking mesoporous silica nanostructures (CVSNs) efficiently transport diverse antibiotics across the blood–brain barrier (BBB) into brain parenchyma and cerebrospinal fluid. By enhancing delivery to microglia and astrocytes, CVSNs improve antibiotic bioavailability and therapeutic efficacy against both Gram‐negative and Gram‐positive ...
Qianqian Xu +11 more
wiley +1 more source
von Willebrand Factor and ADAMTS13 Predict Therapeutic Efficacy and Severe Adverse Events in Advanced Hepatocellular Carcinoma Treated With Atezolizumab-Bevacizumab. [PDF]
Nishimura N +12 more
europepmc +1 more source
Intelligent Field‐Adaptive Electrohydrodynamic Printing for Curved Conformal Electronics
To mitigate residual‐charge accumulation and spatial electric‐field variations during electrohydrodynamic printing on curved insulating substrates, an intelligent field‐adaptive framework combines alternating‐electric‐field modulation, equivalent electrical gap characterization, and machine‐learning‐guided parameter inversion and pathwise regulation ...
Chang Liu +14 more
wiley +1 more source
Hypothalamic POMC Neurons Gate the Fear‐Feeding Trade‐Off
Hungry animals must continually arbitrate between feeding and defensive behaviors when confronted with potential threats. We show that hypothalamic POMC neurons engage CRH‐expressing stress circuits and downstream hormonal responses to coordinate this behavioral selection between competing behaviors.
Cristina Miralpeix +16 more
wiley +1 more source
Large Oncosomes Induce Pro‐Metastatic Stromal‐Myeloid Reprogramming
Large oncosomes systemically reprogram bone marrow mesenchymal stem cells through innate nucleic acid sensing, driving inflammatory and immunosuppressive remodeling that supports a metastasis‐permissive bone marrow environment, revealing a novel tumor‐host communication axis in cancer. ABSTRACT Bone metastasis can be facilitated by systemic remodeling,
Taylon Felipe Silva +18 more
wiley +1 more source
The impact of perioperative adverse events on kidney transplant surgeons: a mixed-methods study. [PDF]
Laverty D +5 more
europepmc +1 more source

