Results 131 to 140 of about 7,188 (177)

The ongoing conundrum of MLL-AF4 driven leukemogenesis

Blood, 2013
In this issue of Blood, Bueno and colleagues explore the developmental impact, as well as the transforming capacity, of the mixed-lineage leukemia (MLL)–AF4 fusion protein in combination with activation of FMS-like tyrosine receptor 3 (FLT3) in human embryonic stem cells (hESCs ...
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Octafluoro[2.2]paracyclophane (AF4) Quinone

Collection of Czechoslovak Chemical Communications, 2008
Octafluoro[2.2]paracyclophane (AF4) has been oxidized by treatment with HIO3 in CF3CO2H to form the corresponding p-quinone along with a unique triketone. This quinone undergoes reduction to the respective hydroquinone as well as a Diels-Alder reaction with 1,3-cyclohexadiene.
Wei Xu, William R. Dolbier, Jian-Xin Duan, Yian Zhai, Katsu Ogawa, Merle A. Battiste, Ion Ghiviriga   +6 more
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A novel MLL/AF4 fusion gene lacking theAF4 transactivating domain in infant acute lymphoblastic leukemia

Blood, 2002
Southern anal. of the MLL Locus in DNA from bone marrow cells samples from a 5-mo old child with acute lymphoblastic leukemiasampled at diagnosis revealed a rearrangement at locus MLL of chromosome 11q23. Panhandle PCR amplification of the fragment comprising the der(11) translocation breakpoints yielded a 4.6 kb fragment corresponding to the bamHI ...
Fabrizio Pane, Mariano Intrieri, Barbara Izzo, Concetta Quintarelli, Domenico Vitale, Roberta Migliorati, Lucia Sebastio, Francesco Salvatore   +7 more
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Alert and sniffy-nosed about Mll-AF4?

Blood, 2006
Comment on Chen et al, page [669][1] A report from the Kersey laboratory documents the long-awaited successful establishment of a murine model for leukemogenesis by the Mll-AF4 fusion gene. The MLL gene is notorious for its promiscuous fusion with multiple alternative partner genes in leukemia,
Mel Greaves, C. W. Eric So
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MLL-AF4 Gene Fusions in Normal Newborns

Blood, 1999
To the Editor: Uckun et al[1][1] have reported that bona fide in-frame fusion MLL-AF4 fusion sequences are detectable, using a sensitive nested reverse transcription-polymerase chain reaction (RT-PCR) method, in around 25% of normal fetal bone marrow and liver samples and in 1 of 6 infant ...
M.-H. Kim-Rouille, A. MacGregor, L.M. Wiedemann, M.F. Greaves, C. Navarrete   +4 more
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The AF4/AF4-MLL interactome

Klinische Pädiatrie, 2011
B Scholz, T Rößler, A Benedikt, T Dingermann, R Marschalek   +4 more
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Authors’ comments: t(4;11) leukemias display addiction to MLL-AF4 but not to AF4-MLL

Leukemia Research, 2011
Ashish R, Kumar, Qing, Yao, Quanzhi, Li, Thien A, Sam, John H, Kersey   +4 more
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Spectroscopic ellipsometry study of parylene AF4

2022 45th International Spring Seminar on Electronics Technology (ISSE), 2022
Dmytro Solonenko, Madeleine Petschnigg, Thang Duy Dao, Goran Miskovic   +3 more
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The protein-protein interaction network within human AF4 and AF4-MLL protein complexes

Klinische Pädiatrie, 2012
T Rössler, B Scholz, T Dingermann, R Marschalek   +3 more
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The human AF4 and AF4·MLL multiprotein complexes provide functions in transcription and epigenetic processes

Klinische Pädiatrie, 2009
A Benedikt, S Baltruschat, TN Arrey, B Meyer, M Karas, A Bursen, T Dingermann, R Marschalek   +7 more
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