Results 11 to 20 of about 526 (116)

From darkness to light: Case report on afamelanotide-treatment in a 9-year-old child with erythropoietic protoporphyria [PDF]

JAAD Case Reports
Anna-Elisabeth Minder, MD, Jasmin Barman-Aksözen, PhD   +1 more
doaj   +2 more sources

Letter to the Editor – Qualitative evidence submitted by patients to NICE: need for more quality or unrealistic and unfair requirements? [PDF]

Journal of Comparative Effectiveness Research
Rocco Falchetto, Jasmin Barman-Aksözen
doaj   +2 more sources

Multifactorial Perspective for Greening Solid-Phase Peptide Synthesis: Rigid Polyacrylate Macroporous Resin in Combination with Green Solvents. [PDF]

ChemSusChem
A rigid, non‐swelling polyacrylate resin enables greener solid‐phase peptide synthesis by allowing various green solvents during the peptide synthesis and significantly reduced process mass intensity without compromising peptide synthesis efficiency/purity.
Noki S, Kumar A, Zhang C, Basso A, Serban S, Kou X, Li Y, Sharma A, de la Torre BG, Albericio F.   +9 more
europepmc   +2 more sources

Silica-Assisted Solid-Phase Peptide Synthesis (SiPPS). [PDF]

J Pept Sci
The use of a non‐swelling resin for solid‐phase peptide synthesis allows the reduction of solvent consumption by up to 50%. ABSTRACT Non‐swelling silica‐based resin was used for peptide synthesis. The strategy used is similar to that of solid‐phase peptide synthesis (SPPS), referred to as silica‐assisted solid‐phase peptide synthesis (SiPPS).
Nkwanyana N, Kumar A, Chakraborty A, Potvin S, Thibaut-Koumba G, Nardone B, Beland F, Sharma A, de la Torre BG, Albericio F.   +9 more
europepmc   +2 more sources

Computational Screening of Approved Drugs for Inhibition of the Antibiotic Resistance Gene mecA in Methicillin-Resistant Staphylococcus aureus (MRSA) Strains

BioTech, 2023
Antibiotic resistance is a critical problem that results in a high morbidity and mortality rate. The process of discovering new chemotherapy and antibiotics is challenging, expensive, and time-consuming, with only a few getting approved for clinical use.
Benson Otarigho, Mofolusho O. Falade
doaj   +1 more source

Adjunctive use of Polypodium leucotomos extract in patients with erythropoietic protoporphyria: An exploratory study. [PDF]

Photochem Photobiol
Erythropoietic protoporphyria (EPP) and X-linked protoporphyria (XLP) cause severe photosensitivity, resulting in significant quality of life (QoL) impairment.
Shetty N, Quiñonez RL, Ceresnie MS, Ghosh S, Lim HW, Mohammad TF.   +5 more
europepmc   +2 more sources

Erythropoietic protoporphyria in the Netherlands:Clinical features, psychosocial impact and the effect of afamelanotide [PDF]

, 2023
Erythropoietic protoporphyria (EPP) patients experience severe burning pain after light exposure, which results in a markedly reduced quality of life. However, there is limited information on the psychosocial aspects of EPP.
Langendonk, Janneke G; id_orcid, Wagenmakers, Margreet A.E.M., Wensink, Debby, J. H. Paul Wilson, Janneke G. Langendonk, Debby Wensink, Margreet A. E. M. Wagenmakers, Wilson, J. H.Paul   +7 more
core   +1 more source

Medicaments and oral healthcare. Hyperpigmentation of oral soft tissues due to afamelanotide [PDF]

, 2020
The medicament afamelanotide is an analogue of endogenous ?-melanocyte-stimulating hormone. It promotes cutaneous pigmentation, providing protection from sunlight. In dermatology, afamelanotide seems to establish therapeutic results for polymorphic light
Vissink, A; id_orcid, Zweers, P G M A, Phoa, K H, de Baat, C, Rozema, F R, Bolling, M C, Vissink, A., Bolling, M., Zweers, P.G.M.A., Rozema, F.R., de Baat, C., Phoa, K.H.   +11 more
core   +1 more source

Characteristics of childhood vitiligo and the progress of its treatment

Pifu-xingbing zhenliaoxue zazhi, 2022
Vitiligo is a common depigmentation disease. Childhood vitiligo exhibits some characteristics in epidemiology, clinical manifestations, comorbidities, etc.
Xiuzhen LI, Xiulian XU
doaj   +1 more source

Objective light exposure measurements and circadian rhythm in patients with erythropoietic protoporphyria:A case-control study [PDF]

, 2022
Background: Erythropoietic protoporphyria (EPP) patients suffer from painful phototoxicity. Sunlight-avoiding behaviour has not yet been quantified objectively in EPP patients.
Wagenmakers, Margreet A.E.M., Wensink, Debby, Langendonk, Janneke G.; id_orcid, Qi, Hongchao, Wilson, J. H.Paul, Hongchao Qi, Janneke G. Langendonk, Margreet A.E.M. Wagenmakers, J.H. Paul Wilson, Debby Wensink   +9 more
core   +1 more source