Results 21 to 30 of about 388 (104)
Medicine Access @ Point of Care, 2019 Patient representation during the evaluation of medicines by key decision makers such as regulatory agencies, Health Technology Assessment bodies, and healthcare payers is increasingly considered to add value to the appraisals and empowers patients ...
Jasmin Barman-Aksözen
doaj +1 more source
Health and Quality of Life Outcomes, 2010 Background Protoporphyria (PP) resulting from two rare, inherited diseases of heme biosynthesis leads to dermal phototoxicity by accumulation of the heme precursor protoporphyrin IX.
Minder Christoph E +2 more
doaj +1 more source
Advances in the management of erythropoietic protoporphyria – role of afamelanotide
The Application of Clinical Genetics, 2016 Erythropoietic protoporphyria (EPP) and the phenotypically similar disease X-linked protoporphyria (XLPP) are inherited cutaneous porphyrias characterized clinically by acute non-blistering photosensitivity, intolerance to sunlight, and significantly reduced quality of life.
Ashley Lane +2 more
openaire +5 more sources
An overview of the cutaneous porphyrias [version 1; referees: 2 approved]
F1000Research, 2017 This is an overview of the cutaneous porphyrias. It is a narrative review based on the published literature and my personal experience; it is not based on a formal systematic search of the literature.
Robert Dawe
doaj +1 more source
Advances in the management of erythropoietic protoporphyria – role of afamelanotide
The Application of Clinical Genetics, 2016 Ashley M Lane,1 Jerome T McKay,2 Herbert L Bonkovsky1 1Department of Internal Medicine, Section on Gastroenterology; 2Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, NC, USAAbstract ...
Lane AM, McKay JT, Bonkovsky HL
doaj
Afamelanotide and Narrowband UV-B Phototherapy for the Treatment of Vitiligo [PDF]
JAMA Dermatology, 2015 Narrowband UV-B (NB-UV-B) phototherapy is used extensively to treat vitiligo. Afamelanotide, an analogue of α-melanocyte-stimulating hormone, is known to induce tanning of the skin.To evaluate the efficacy and safety of combination therapy for generalized vitiligo consisting of afamelanotide implant and NB-UV-B phototherapy.This study was performed in ...
Henry W, Lim +7 more
openaire +2 more sources
Toward sustainable solid-phase peptide synthesis strategy – in situ Fmoc removal
Green Chemistry Letters and ReviewsSolid-phase peptide synthesis (SPPS) is the method of choice for the synthesis of peptides for research and production purposes. Despite having several positive features, it remains a challenge to reduce the amount of solvent waste generated during the ...
Ndumiso Mthethwa +5 more
doaj +1 more source
Green Chemistry Letters and ReviewsThe free use of DMF has recently been restricted since December 2023 in Europe because of its health hazards. Over time, these restrictions will extend to the USA and other countries.
Sikabwe Noki +6 more
doaj +1 more source
Polymorphism of Melanocortin Receptor Genes—Association with Inflammatory Traits and Diseases
DiseasesMelanocortin receptors (MCRs) are responsible for various functions ranging from skin pigmentation, regulation of appetite, stress response and cognition, steroid synthesis, and energy balance to cellular regeneration and immunomodulation.
Mainak Bardhan +12 more
doaj +1 more source
JAMA Dermatology, 2020 The effectiveness of afamelanotide treatment in patients with erythropoietic protoporphyria (EPP) in clinical practice who experience pain after light exposure that substantially impairs quality of life is unknown.To evaluate the association of afamelanotide treatment with outcomes in patients with EPP in regular practice during longer-term follow-up ...
Wensink, Debby +6 more
openaire +4 more sources