Results 121 to 130 of about 12,727,021 (363)

Single cis‐elements in brassinosteroid‐induced upregulated genes are insufficient to recruit both redox states of the BIL1/BZR1 DNA‐binding domain

open access: yesFEBS Letters, EarlyView.
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki   +4 more
wiley   +1 more source

Affect and Dialogue in Collaborative Cross- Disciplinary Research: Developing Interactive Public Art on Cardiff Bay Barrage

open access: yesOpen Cultural Studies, 2017
Where Cartesian philosophy distinguishes the perceiving and perceptual mind from the body, phenomenology constitutes the experiential/experiencing body as the subject, giving rise to the affective potential of art.
Entwistle Alice   +5 more
doaj   +1 more source

Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment

open access: yesFEBS Letters, EarlyView.
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke   +2 more
wiley   +1 more source

Exploring the prospects, advancements, and challenges of in vitro modeling of the heart-brain axis

open access: yesFrontiers in Cellular Neuroscience
Research on bidirectional communication between the heart and brain has often relied on studies involving nonhuman animals. Dependance on animal models offer limited applicability to humans and a lack of high-throughput screening.
Senegal Alfred Mabry, Narciso Pavon
doaj   +1 more source

Choreographies of Protest Performance as Recruitment to Activism

open access: yesJournal of Student Affairs in Africa, 2021
This article seeks to understand why some bystanders to protest transcended to become actors in protests during the re-emergence of wide-spread student activism in an institution of higher education in South Africa during 2015.
Phiwokazi Qoza
doaj  

A working model for cytoplasmic assembly of H/ACA snoRNPs

open access: yesFEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

Manifold invariants affect dynamics in ADS gravity

open access: yes, 2012
The first-order Holst action with negative cosmological constant is rendered finite by requiring functional differentiability on the configuration space of tetrads and connections. The surface terms that arise in the action for ADS gravity are equivalent
Liko, Tomas
core   +1 more source

Affective Relevance [PDF]

open access: yesIEEE Intelligent Systems
Modeling information relevance aims to construct a conceptual understanding of information significant for users’ goals. Today, myriad relevance estimation methods are extensively used in various systems and services, mostly using behavioral signals such as dwell-time and click-through data and computational models of visual or textual correspondence ...
Tuukka Ruotsalo   +3 more
openaire   +2 more sources

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

open access: yesFEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer   +10 more
wiley   +1 more source

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