Results 131 to 140 of about 12,945,328 (314)

Feeling Is First

Arts
Within the fields of aesthetics and psychology, there is a long tradition of arguing that affect precedes cognition. A verbalized thought following upon a feeling and associated with it does not translate the feeling precisely or adequately.
Richard Shiff
doaj   +1 more source

Does Health Affect Portfolio Choice? [PDF]

Previous studies find a strong and positive empirical connection between health status and the share of risky assets held in household portfolios.
David Love, Paul A. Smith
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Toward a politics of shame: cripping understandings of affect in disabled people’s encounters with unsolicited advice

Frontiers in Sociology
The prevalence of unsolicited advice in the lives of disabled people is well-catalogued in the mass of articles and social media posts dedicated to the issue.
Megan Ingram
doaj   +1 more source

Multiple Factors Affect Job Satisfaction of Hospital RNs [PDF]

, 2007
Highlights findings from an analysis of variables associated with job satisfaction levels of registered nurses working in hospitals, including health status, race/ethnicity, career orientation, working conditions, workload, and ...
Carol Brewer, Christine Kovner, Deanna Lewis   +2 more
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Is There a Spinozist Concept of Recognition?

Journal of Spinoza Studies
Among modern pre-Hegelian philosophers, the term recognition does not designate recognition in the Hegelian sense of the value of freedom, but the “gratitude” felt for a gift or service rendered that requires reciprocity.
Christian Lazzeri
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Does welfare reform affect fertility? Evidence from the UK [PDF]

, 2007
In 1999 the UK government made major reforms to the system of child-contingent benefits, including the introduction of Working Families’ Tax Credit and an increase in means-tested Income Support for families with children.
Brewer, M., Ratcliffe, A., Smith, S.
core   +1 more source