Results 171 to 180 of about 12,727,021 (363)

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Influences which affect the form of the respiratory cycle, in particular that of the expiratory phase

, 1933
M. Hammouda, W. H. Wilson
openalex   +2 more sources

THE FERTILISERS AND FEEDING STUFFS ACT, 1926, AS IT AFFECTS THE SALE OF BREWERY AND MALTINGS BY-PRODUCTS [PDF]

, 1929
H. Lloyd Hind
openalex   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

ON THE VENOUS CIRCULATION IN RELATION TO SOME OF THE DISEASES WHICH AFFECT THE LOWER LIMB. [PDF]

, 1877
John Gay
openalex   +2 more sources

Multiple Turning and Orienting Eggs During Incubation as They Affect Hatchability

, 1936
Marlow W. Olsen, T. C. Byerly
openalex   +1 more source

SOME OF THE INFLUENCES WHICH AFFECT THE POWER OF VOLUNTARY CONTRACTION [PDF]

, 1892
JC
openalex   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

Further Tests of the Metacognitive Advantage Model: Counterfactuals, Confidence and Affect

Psychological Topics, 2019
This study tested whether people have an accurate sense of how good their reasoning is, as measured by their confidence in their responses, and how good they feel after they give those responses.
André Mata
doaj  

DO THE MINING OPERATIONS AFFECT THE CLIMATE OF KIMBERLEY? [PDF]

, 1900
J. R. Sutton
openalex   +1 more source