Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
The Influence of Deep Space and the Stars on Emotions. [PDF]
Int J PsycholMartens JP, Prokopetz M, Tomlinson K.
europepmc +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Latent profiles of exercise motivation and exercise-induced emotions: associations with physical activity and gender among Chinese college students. [PDF]
Front PsycholDai Y, Zhao Y, He P.
europepmc +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Response: Commentary: Outlining a novel psychometric model of mental flexibility and affect dynamics
Frontiers in PsychologyFrancesca Borghesi +2 more
doaj +1 more source
The Relationship Between Identity-Based Social Support, Victimization, and Mental Health among LGBTQ+ Youth. [PDF]
Psychol Sex Orientat Gend DiversMermin Z, Gallagher NM, Olson K.
europepmc +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Correlation of physical activity with positive and negative affect and frontal lateralization in college students with depressive symptoms. [PDF]
Sci RepZhong X, Ren Y, Liu C, Cao N.
europepmc +1 more source
An integrative head-heart-hands model of moral education: evidence from Chinese higher education. [PDF]
Front PsycholWang M, Saharuddin N, Yasin M, Chen X.
europepmc +1 more source