Results 211 to 220 of about 4,712,758 (317)
openaire +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
A mediation model explaining the impact of fear of COVID-19 and COVID-19- induced changes in multiple life domains on adolescents' subjective well-being in sub-Saharan Africa. [PDF]
Addae EA +4 more
europepmc +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Emoji or real emotions? The effect of digitalization on the quality of life through social media addiction - a multigroup SEM analysis, moderated by positive and negative affect. [PDF]
Lițan DE.
europepmc +1 more source
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Social Mismatch and Affective Wellbeing: An Ecological Momentary Assessment Study. [PDF]
de Vries LP, Bartels M.
europepmc +1 more source

