Results 131 to 140 of about 1,367,904 (292)

INAPPROPRIATE AFFECT [PDF]

open access: yesJournal of Neurology, Neurosurgery & Psychiatry, 1956
A, HARRIS, M, METCALFE
openaire   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

In the mood to innovate : a multilevel study on the interaction of entrepreneurs' innovative work behaviour and affect : a dissertation presented in partial fulfilment of the requirements for the degree of Master of Business Studies in Management, Massey University, Wellington, New Zealand [PDF]

open access: yes, 2016
Affect is a hot topic in entrepreneurial research. However, extant literature is lagging behind in its use of affective theory and methodology, and furthermore, attention resides in isolated topics of inquiry, rendering the field stunted and disjointed ...
Williamson, Amanda J
core  

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Post-Theory and Beyond

open access: yesRevista Brasileira de Literatura Comparada
This article surveys and assesses the eclectic trends in literary theory and criticism in the posttheory age with a focus on three rubrics: the cultural turn, the historic turn, and the affective turn.
Luiz Fernando Valente
doaj  

Exploring Features and Products in E-Commerce on Consumers Behavior Using Cognitive Affective

open access: yesIEEE Access
Technology advancement has given rise to a new online purchasing paradigm known as e-commerce. Online shopping in e-commerce platform has altered consumer behavior and purchasing decisions.
Pahrudin Pahrudin   +5 more
doaj   +1 more source

TQM practices and affective commitment: a case of Malaysian semiconductor packaging organizations [PDF]

open access: yes
The purpose of the present study is to examine the effects of the five elements of TQM practices on employees’ affective commitment within six major Malaysian semiconductor contract manufacturing organizations. Despite extensive research on TQM practices,
Arumugam, Veeri   +2 more
core   +1 more source

Neural Basis of Motivation Lateralizes with Motor Control [PDF]

open access: yes, 2011
According to decades of research on affective motivation in the human brain, approach motivational states are subserved by the left hemisphere and avoidance states by the right hemisphere.
Daniel Casasanto, Geoffrey Brookshire
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

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