Results 131 to 140 of about 1,377,205 (292)
Journal of Neurology, Neurosurgery & Psychiatry, 1956 A, HARRIS, M, METCALFE
openaire +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
The Influence of Job Satisfaction and Organizational Commitment on Executive Withdrawal and Performance [PDF]
, 2000 This research examines the influence of job satisfaction and three dimensions of organizational commitment (i.e., affective, continuance, and normative) on the intention to leave, job search activity, performance, and leadership effectiveness of ...
Boswell, Wendy R. +2 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
TQM practices and affective commitment: a case of Malaysian semiconductor packaging organizations [PDF]
The purpose of the present study is to examine the effects of the five elements of TQM practices on employees’ affective commitment within six major Malaysian semiconductor contract manufacturing organizations. Despite extensive research on TQM practices,
Arumugam, Veeri +2 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The affective discourse dynamics of metaphor clustering
Ilha do Desterro, 2007 <p align="left">Metaphor is examined in the very different iscourse contexts of the classroom and of reconciliation talk to highlight the neglected affective dimension.
Lynne Cameron
doaj
Journal of Nursing PracticeBackground: Breast cancer is a significant health concern among Indonesian women, emphasizing the need for effective prevention strategies. Purpose: This study investigates the effects of health education utilizing the Breast Self-Examination (BSE ...
Nurullita Widyazizah +2 more
doaj +1 more source
Neural Basis of Motivation Lateralizes with Motor Control [PDF]
, 2011 According to decades of research on affective motivation in the human brain, approach motivational states are subserved by the left hemisphere and avoidance states by the right hemisphere.
Daniel Casasanto, Geoffrey Brookshire
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FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source