Results 91 to 100 of about 339,002 (305)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Trust and Commitment in Professional Service Marketing Relationships in Business-to-Business Markets [PDF]

open access: yes
This paper examines two very important concepts in marketing relationships – trust and commitment – whereby commitment is regarded as consisting of three components: affective, calculative and normative. The context of this study is professional services
Barbara Cater
core  

PENGARUH KARAKTERISTIK PEKERJAAN TERHADAP MOTIVASI INTRINSIK UNTUK BERBAGI PENGETAHUAN SECARA ONLINE DENGAN MENGGUNAKAN AFFECTIVE COMMITMENT SEBAGAI VARIABEL MEDIASI (STUDI PADA KARYAWAN PT. PERTAMINA (PERSERO) ACEH) [PDF]

open access: yes, 2017
ABSTRAK Penelitian ini bertujuan untuk mengetahui pengaruh dari Karakteristik Pekerjaan terhadap Motivasi Intrinsik untuk berbagi pengetahuan secara onlinedengan menggunakan Affective Commitment sebagai mediasi. Sampel yangdigunakan dalam penelitian ini
Rahmad Rizki
core  

Intrinsic Motivation, Job Autonomy and Turnover Intention in the Italian Healthcare: The mediating role of Affective Commitment [PDF]

open access: yes, 2011
Drawing on Self-Determination and Work Characteristics theories, we hypothesized that job autonomy and intrinsic motivation were key exogenous variables positively related to affective commitment, which in turn is negatively related to turnover ...
BATTISTELLI A.   +2 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

A study of the relationship between educational climate and intrinsic motivation to study with students' affective commitment: case study engineering college of Shiraz University

open access: yesآموزش مهندسی ایران, 2014
The main purpose of this research was to investigate the relationship between educational climate and intrinsic motivation to study with engineering students' affective commitment in Shiraz University. Statistical population is whole of bachelor students
Mahdi Mohammadi, Zenab Peyravi Nejad
doaj   +1 more source

Analisa Pengaruh Percieved Organizational Support Terhadap Performance Melalui Affective Commitment Sebagai Variabel Mediasi Di Pizza Hut Raya Kupang Indah Surabaya [PDF]

open access: yes, 2015
Performance merupakan salah satu aspek terpenting yang harus dimiliki oleh seluruh karyawan dalam suatu organisasi. Dalam penelitian kali ini, peneliti menggunakan affective commitment sebagai variabel yang mempengaruhi performance pada karyawan Pizza ...
Gunawan, J. S. (Jeffran)   +2 more
core  

Participative Leadership and the Organizational Commitment of Civil Servants in China: The Mediating Effects of Trust in Supervisor [PDF]

open access: yes, 2013
The present study examines whether participative leadership engenders organizational commitment among Chinese civil servants, and analyzes the mechanisms by which it transmits its effects.
Miao, Qing   +3 more
core   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

The Psychology Behind Commitment And Loyalty - An Empirical Study In A Bank Setting [PDF]

open access: yes
Despite the extant literature on customer loyalty, it is recognized that the psychological processes behind commitment and customer loyalty are still ill understood.
Bloemer,Josée   +2 more
core   +1 more source

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