Results 101 to 110 of about 40,297 (307)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Employee Participation, Trust and Affective Commitment
, 2012 Human capital enhances corporate competitiveness. In order to retain talent within organization, employee attitude becomes a critical issue. This study investigates the relationship between employee participation, trust and affective commitment.
Lin, Ku-jun; Huang, Yen-lin, Lin, Ku-jun
core
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Customer relationship management for brand commitment and brand loyalty
, 2015 This article examined the impact of customer relationship management strategy on customers brand commitment and brand loyalty in the Nigeria financial sector.
Wright, Len +3 more
core
Affective commitment to the employer brand: development and validation of a scale
, 2016 In recent years employer branding has become increasingly important as a source of sustainable competitive advantage. Companies are trying to engender affective commitment in the best employees in a global labor market.
Blasco López, María Francisca +3 more
core +1 more source
Managerial Factors and Organisational Commitment: A Comparative Study of Police Officers and Civilian Staff [PDF]
, 2001 Civilian workers have become a progressively larger proportion of UK Police Forces employment yet there is very little research on this group of workers and none other than this article that compares and contrasts civilian and police officers experience ...
Dick, Gavin P.M., Metcalfe, Beverley
core +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Work-family Conflict and Organisational Commitment in Malaysia
, 2014 This study examined the relationship between work-family conflict (WFC) and organisational commitment, and considered gender and number of dependents as moderators.
Siu, Yen Pin
core
Middle managers’ role in organizational commitment and organizational citizenship behaviours [PDF]
, 2015 “Any motivated behavior, either preparatory or consummatory, must be understood to be a channel through which many basic needs may be simultaneously expressed or satisfied.
Landa, Clive H.
core
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source