Results 81 to 90 of about 40,297 (307)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
The effects of compassion experienced by SME employees on affective commitment: Double-mediation of authenticity and positive emotion [PDF]
Management Science Letters, 2019 The purpose of this study is to empirically examine the effects of compassion experienced by small-to-medium enterprise (SME) employees on affective commitment through authenticity and positive emotion. This study was conducted with 200 employees working
Sung-Hoon Ko, Yongjun Choi
doaj +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Cogent Social SciencesPublic relations’ fundamental functions date back to the dawn of human civilisation. The study assessed the relationship between public relation, corporate image and customer affective commitment at MTN in Ghana.
Benedict Ofori Antwi +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
, 2008 The purpose of this research was to identify motivational factors that would predict organisational commitment and citizenship behaviour. One important motivational factor is empowerment, which is an intrinsic motivator (Spreitzer, 1995, p. 121 table 5 ),
Rodriguez-Llewell, Yanahina
core
Identification-commitment inventory (ICI model): confirmatory factor analysis and construct validity
, 2010 Organizational commitment, Organizational identification, Confirmatory factor analysis, Structural equation modeling, Elliptical least square solution,
Yepes i Baldó, Montserrat +9 more
core +1 more source
Transparency in managerial practices and affective commitment
Journal of Business Studies, 2019 The objective of this study was to investigate the relationship between employees’ perception of transparency in management and their affective commitment by focusing on four dimensions of management transparency: openness, accountability, integrity and participation.
Kandiah Jenat Bratley +1 more
openaire +2 more sources
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source