Results 71 to 80 of about 7,446,825 (333)

Lipid oxidation in young patients with newly diagnosed bipolar disorder and their relatives

International Journal of Bipolar Disorders
Background Oxidative stress may be involved in the pathophysiology of bipolar disorder (BD). Malondialdehyde (MDA), a product of fatty acid peroxidation has been proposed as a trait marker of BD associated with familial risk.
Sharleny Stanislaus, Klara Coello, Hanne Lie Kjaerstad, Kimie Stefanie Ormstrup Sletved, Kamilla Woznica Miskowiak, Maria Faurholt-Jepsen, Klaus Munkholm, Henrik Enghusen Poulsen, Maj Vinberg, Jens Lykkesfeldt, Lars V. Kessing   +10 more
doaj   +1 more source

CACNA1C polymorphisms Impact Cognitive Recovery in Patients with Bipolar Disorder in a Six-week Open-label Trial

Scientific Reports, 2017
Cognitive impairments in bipolar patients deteriorate as the disorder progresses. Little is known about whether genetic risks impact cognitive recovery during the course from depression to remission.
Kangguang Lin, Guiyun Xu, Lingling Shi, Weicong Lu, Lijie Guan, Huiyi Ouyang, Kun Chen, Yamei Dang, Libing Zhou, Kwok-Fai So   +9 more
doaj   +1 more source

Communication Styles of Children of Mothers with Affective Disorders, Chronic Medical Illness, and Normal Controls: A Contextual Perspective

, 1993
Research has demonstrated impaired parent-child relationships in families with affective disorders. The present study examines the association of children\u27s interactional style during a direct conflict-solving task to both the mother\u27s ...
Hamilton, Elizabeth Burney, Hammen, Constance, Jones, Maren, Minasian, Gayane   +3 more
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Neural mechanisms of affective instability and cognitive control in substance use

, 2019
Objective: We explored the impact of affect on cognitive control as this relates to individual differences in affective instability and substance use.
Bodkyn, Carmen N., Holroyd, Clay
core   +1 more source

Transdiagnostic treatment of bipolar disorder and comorbid anxiety using the Unified Protocol for Emotional Disorders: A pilot feasibility and acceptability trial [PDF]

, 2017
BACKGROUND Comorbid anxiety in bipolar disorder (BD) is associated with greater illness severity, reduced treatment response, and greater impairment. Treating anxiety in the context of BD is crucial for improving illness course and outcomes. The current
Baek, Ji Hyun, Barlow, David H., Bernstein, Emily E., Deckersbach, Thilo, Ellard, Kristen K., Hearing, Casey, Nierenberg, Andrew A., Sylvia, Louisa G.   +7 more
core   +1 more source

Mood Reactivity and Affective Dynamics in Mood and Anxiety Disorders

Journal of Abnormal Psychology, 2018
The application of ecological momentary assessment (EMA) in community settings provides a powerful opportunity to obtain measures of emotional reactivity to daily life events, as well as emotional dynamics in real time.
F. Lamers, J. Swendsen, L. Cui, M. Husky, Jordan T. Johns, V. Zipunnikov, K. Merikangas   +6 more
semanticscholar   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Treating the patient not just the disease? : Delving deeper into the possible link between affective disorders and coronary heart disease through statistical analysis of a random sample of Maltese people [PDF]

, 2014
Background: Ischemic heart disease is the leading cause of death in Males in Malta and globally. Affective disorders are the commonest psychological problem.
Calleja, Neville, Debono, David
core  

Behavioural outcomes and psychopathology during adolescence [PDF]

, 2013
Preterm birth is associated with a high risk of residual neurodevelopmental disability and cognitive impairment. These problems are closely associated with psychiatric disorders and thus it is unsurprising that preterm birth also confers high risk for ...
Johnson, Samantha J., Wolke, Dieter
core   +1 more source