Results 91 to 100 of about 533,233 (349)

Lost Toy? Monsters Under the Bed? Contributions of Temperament and Family Factors to Early Internalizing Problems in Boys and Girls [PDF]

, 2011
This study was designed to examine the contribution of multiple risk factors to early internalizing problems and to investigate whether family and ecological context moderated the association between child temperament and internalizing outcomes. A sample
Briggs-Gowan, Margaret J., Carter, Alice S., Marakovitz, Susan E., Mian, Nicholas D., Wagmiller, Robert L.   +4 more
core   +2 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Early maternal relational traumatic experiences and psychopathological symptoms: a longitudinal study on mother-infant and father-infant interactions [PDF]

, 2015
Early maternal relational traumas and psychopathological risk can have an impact on mother-infant interactions. Research has suggested the study of fathers and of their psychological profiles as protection or risk factors.
BALLAROTTO, GIULIA, CERNIGLIA, LUCA, CIMINO, SILVIA, TAMBELLI, Renata   +3 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Recruiting for research studies using online public advertisements examples from research in affective disorders

Neuropsychiatric Disease and Treatment, 2016
Toby Wise,1 Danilo Arnone,1 Lindsey Marwood,1 Roland Zahn,1–3 Karen E Lythe,2,3 Allan H Young1 1Centre for Affective Disorders, Department of Psychological Medicine, Institute of Psychiatry, King’s College London, London ...
Wise T, Arnone D, Marwood L, Zahn R, Lythe K, Young A   +5 more
doaj  

Neural and Behavioral Predictors of Treatment Efficacy on Mood Symptoms and Cognition in Mood Disorders: A Systematic Review

Frontiers in Psychiatry, 2018
Background: The clinical and etiological heterogeneity of mood disorders impede identification of effective treatments for the individual patient. This highlights a need for early neuronal and behavioral biomarkers for treatment efficacy, which can ...
Ida Seeberg, Ida Seeberg, Hanne L. Kjaerstad, Kamilla W. Miskowiak, Kamilla W. Miskowiak   +4 more
doaj   +1 more source

Clozapine as add-on medication in the maintenance treatment of bipolar and schizoaffective disorders - A case series [PDF]

, 2002
Atypical neuroleptics are increasingly used in the treatment of bipolar and schizoaffective disorders. Currently, numerous controlled short-term studies are available for clozapine, olanzapine, risperidone or quetiapine, but long-term data are still ...
Amann, B., Dittmann, Sandra, Forsthoff, A., Grunze, Heinz, Hummel, B., Matzner, N.   +5 more
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Does gaze direction modulate facial expression processing in children with autism spectrum disorder? [PDF]

, 2009
Two experiments investigated whether children with autism spectrum disorder (ASD) integrate relevant communicative signals, such as gaze direction, when decoding a facial expression. In Experiment 1, typically developing children (9–14 years old; n = 14)
Adams, Adams, Adolphs, American Psychiatric Association, Ashwin, Aylward, Back, Barnes, Baron-Cohen, Baron-Cohen, Baron-Cohen, Baron-Cohen, Baron-Cohen, Berument, Blair, Braverman, Brothers, Camras, Caron, Critchley, Dairoku, Dalton, Ekman, Farroni, Field, Field, Frith, Ganel, Grossman, Grossmann, Happé, Harrigan, Haxby, Herba, Hobson, Hobson, Hood, Howard, Japanese WISC-III Publication Committee, Jemel, Johnson, Johnson, Kamio, Kemner, Kleinhans, Klin, Kylliäinen, Kylliäinen, Leekam, Magnée, McIntosh, Nelson, Neumann, Odom, Okada, Ozonoff, Pelphrey, Pelphrey, Pierce, Piggot, Prior, Ristic, Rolls, Sato, Schultz, Schumann, Senju, Senju, Senju, Serrano, Smith, Sparks, Spezio, Striano, Swettenham, Tantam, van der Geest, Vlamings, Watanabe, Wechsler, Weeks, Wicker   +81 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source