Results 1 to 10 of about 491,727 (238)

Subtle Cerebellar Features in Relatives of Essential Tremor Cases

Frontiers in Neurology, 2020
Background: Essential tremor (ET) cases often exhibit a range of mild cerebellar signs. Their unaffected relatives have been shown in prior studies to exhibit subtle (i.e., preclinical) disease features.Objective: To quantify subtle cerebellar signs in ...
Evan A. Hale, Ruby Hickman, Hollie Dowd, Deepti Varathan, Gina Liu, Elan D. Louis, Elan D. Louis, Elan D. Louis, Elan D. Louis   +8 more
doaj   +1 more source

Neurodevelopment regulators miR-137 and miR-34 family as biomarkers for early and adult onset schizophrenia

npj Schizophrenia, 2021
Early-onset schizophrenia (EOS) may have stronger familial aggregation and a more severe outcome than adult-onset schizophrenia (AOS). MicroRNA (miRNA) takes on dual roles as a genetic and epigenetic modulator, which may mediate the influence of genetic ...
Bao-Yu Chen, Jin-Jia Lin, Ming-Kun Lu, Hung-Pin Tan, Fong-Lin Jang, Sheng-Hsiang Lin   +5 more
doaj   +1 more source

Failure to deactivate the default mode network indicates a possible endophenotype of autism

Molecular Autism, 2012
Background Reduced activity during cognitively demanding tasks has been reported in the default mode network in typically developing controls and individuals with autism.
Spencer Michael D, Chura Lindsay R, Holt Rosemary J, Suckling John, Calder Andrew J, Bullmore Edward T, Baron-Cohen Simon   +6 more
doaj   +1 more source

Functional Alterations in Patients with Bipolar Disorder and Their Unaffected First-Degree Relatives: Insight from Genetic, Epidemiological, and Neuroimaging Data

Neuropsychiatric Disease and Treatment, 2023
Haonan Zhang,1 Jun Chen,1,2 Yiru Fang1– 4 1Clinical Research Center, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China; 2Shanghai Key Laboratory of Psychotic Disorders, Shanghai, People ...
Zhang H, Chen J, Fang Y
doaj  

Women Are More Susceptible to Caries but Individuals Born with Clefts Are Not

International Journal of Dentistry, 2011
The identification of individuals at a higher risk of developing caries is of great interest. Isolated forms of cleft lip and palate are among the most common craniofacial congenital anomalies in humans.
Aditi Jindal, Michelle McMeans, Somnya Narayanan, Erin K. Rose, Shilpa Jain, Mary L. Marazita, Renato Menezes, Ariadne Letra, Flavia M. Carvalho, Carla A. Brandon, Judith M. Resick, Juan C. Mereb, Fernando A. Poletta, Jorge S. Lopez-Camelo, Eduardo E. Castilla, Iêda M. Orioli, Alexandre R. Vieira   +16 more
doaj   +1 more source

Reduced anti-Müllerian hormone levels in males with inherited bone marrow failure syndromes

Endocrine Connections
Fanconi anemia (FA), dyskeratosis congenita-related telomere biology disorders (DC/TBD), and Diamond–Blackfan anemia (DBA) are inherited bone marrow failure syndromes (IBMFS) with high risks of bone marrow failure, leukemia, and solid tumors. Individuals
Pamela Stratton, Neelam Giri, Sonia Bhala, Martha M Sklavos, Blanche P Alter, Sharon A Savage, Ligia A Pinto   +6 more
doaj   +1 more source

Early Head Tremor in Essential Tremor: A Case Series and Commentary

Tremor and Other Hyperkinetic Movements, 2017
Background: Classically, the onset of head tremor in essential tremor (ET) patients follows that of hand tremor, such that there is a somatotopic spread of involved areas.
Elan D. Louis, Funmi M. Badejo, Ashley D. Cristal, James Meyers, Nora Hernandez, Karen P. Chen, Kelly V. Naranjo, Jemin Park, Lorraine N. Clark   +8 more
doaj   +1 more source

Age-related sexual dimorphism in temporal discrimination and in adult-onset dystonia suggests GABAergic mechanisms.

Frontiers in Neurology, 2015
Background: Adult onset isolated focal dystonia presenting in early adult life is more frequent in men whereas in middle age it is female predominant.
John S. Butler, Ines M Beiser, Ines M Beiser, Laura eWilliams, Laura eWilliams, Eavan eMcGovern, Eavan eMcGovern, Fiona eMolloy, Tim eLynch, Daniel G Healy, Helena eMoore, Richard eWalsh, Richard B Reilly, Richard B Reilly, Sean eO'Riordan, Sean eO'Riordan, Cathal eWalsh, Cathal eWalsh, Michael eHutchinson, Michael eHutchinson   +19 more
doaj   +1 more source

Associations between N-Acetylaspartate and white matter integrity in individuals with schizophrenia and unaffected relatives. [PDF]

Psychiatry Res Neuroimaging, 2023
Roberts D, Rösler L, Wijnen JP, Thakkar KN.   +3 more
europepmc   +1 more source

Facial emotion-recognition deficits in patients with schizophrenia and unaffected first-degree relatives

Frontiers in Psychiatry
IntroductionThis study aimed to determine trait- and state-dependent markers of schizophrenia by investigating facial emotion-recognition (FER) deficits in remitted patients with schizophrenia and their first-degree relatives (FR).MethodsThree groups ...
Minjae Bae, Minjae Bae, Jihyun Cho, Jihyun Cho, Seunghee Won, Seunghee Won   +5 more
doaj   +1 more source