Results 31 to 40 of about 103,359 (288)
Error-related brain activity as a transdiagnostic endophenotype for obsessive-compulsive disorder, anxiety and substance use disorder [PDF]
, 2019 Background Increased neural error-signals have been observed in obsessive-compulsive disorder (OCD), anxiety disorders, and inconsistently in depression. Reduced neural error-signals have been observed in substance use disorders (SUD). Thus, alterations
Bey, Katharina +8 more
core +1 more source
Frontiers in Psychology, 2022 Few studies have explored the differences in clinical psychopathology between youth at high risk for psychosis and those at familial high risk for psychosis.
Lourdes Nieto +5 more
doaj +1 more source
Autoimmunity to tropomyosin isoforms in ulcerative colitis (UC) patients and unaffected relatives [PDF]
Clinical and Experimental Immunology, 1998 SUMMARYAutoimmunity to cytoskeletal protein tropomyosin (TM) has been demonstrated in UC. However, the TM isoforms involved in this IgG-mediated autoimmune response in UC and the possible presence of serum IgG antibodies against TM (hTMs IgG) in unaffected UC relatives are unknown.
L, Biancone +3 more
openaire +2 more sources
Frontiers in Psychiatry, 2013 Neuroimaging studies have revealed significant reductions in the grey matter of several brain regions in patients with schizophrenia, a neuropsychiatric disorder with high hereditability.
Yuan eXiao +4 more
doaj +1 more source
Visual attention in autism families: ‘unaffected’ sibs share atypical frontal activation [PDF]
, 2009 Background: In addition to their more clinically evident abnormalities of social cognition, people with autism spectrum conditions (ASC) manifest perturbations of attention and sensory perception which may offer insights into the underlying neural ...
Baron-Cohen, S, Belmonte, MK, Gomot, M
core +1 more source
Autonomic Dysfunction in Unaffected First-Degree Relatives of Patients Suffering From Schizophrenia [PDF]
Schizophrenia Bulletin, 2009 Recent studies revealed cardiac autonomic dysfunction in patients with acute schizophrenia, which appears to be mainly related to reduced vagal and increased sympathetic modulation. To understand the significance of cardiac autonomic function in patients with schizophrenia, we extended these studies to relatives of patients.
Karl-Jürgen, Bär +9 more
openaire +2 more sources
Sichuan jingshen weisheng, 2021 ObjectiveTo study the prospective memory deficits of obsessive-compulsive disorder patients and unaffected first-degree relatives of patients， so as to validate the possibility of prospective memory as an endophenotype of obsessive-compulsive disorder ...
Wei Zhen +3 more
doaj +1 more source
Impaired response inhibition and excess cortical thickness as candidate endophenotypes for trichotillomania. [PDF]
, 2014 Trichotillomania is characterized by repetitive pulling out of one's own hair. Impaired response inhibition has been identified in patients with trichotillomania, along with gray matter density changes in distributed neural regions including frontal ...
Chamberlain, Samuel R. +4 more
core +3 more sources
Olfactory function in patients with nonsyndromic orofacial clefts and their unaffected relatives [PDF]
American Journal of Medical Genetics Part A, 2018 Nonsyndromic orofacial clefting is one of the most frequently occurring congenital conditions. The aim of the study was to investigate the prevalence and nature of reduced olfactory function in patients with nonsyndromic cleft lip and/or cleft palate (NSCL/P) and their unaffected first‐degree relatives.
Roosenboom, Jasmien +10 more
openaire +3 more sources
Microstructural Correlates of Resilience against Major Depressive Disorder: Epigenetic Mechanisms? [PDF]
, 2010 Mental disorders are a major cause of long-term disability and are a direct cause of mortality, with approximately 800.000 individuals dying from suicide every year worldwide - a high proportion of them related to major depressive disorder (MDD)^1 ...
Andrew Fagan +8 more
core +3 more sources