Results 41 to 50 of about 491,727 (238)

Saccadic distractibility is elevated in schizophrenia patients, but not in their unaffected relatives [PDF]

, 2005
Background. Saccadic distractibility, as measured by the antisaccade task, has attracted attention as a putative endophenotypic marker for schizophrenia.
Simon, H, Zanelli, J W, Maccabe, J H; id_orcid, Walwyn, R, Murray, R M, McDonald, C D   +5 more
core   +1 more source

Emotional cognition subgroups in unaffected first-degree relatives of patients with mood disorders

, 2023
Background Patients with major depressive disorder (MDD) or bipolar disorder (BD) exhibit difficulties with emotional cognition even during remission. There is evidence for aberrant emotional cognition in unaffected relatives of patients with these mood ...
Miskowiak, Kamilla Woznica, Meluken, Iselin, Vieta, Eduard, Vinberg, Maj, Kessing, Lars Vedel, Varo, Cristina, Kjærstad, Hanne Lie   +6 more
core   +1 more source

Pathways to functional outcome in subjects with schizophrenia living in the community and their unaffected first-degree relatives [PDF]

, 2016
Rationale: Variables influencing real-life functioning have repeatedly been modeled in schizophrenia subjects but not systematically investigated in their unaffected first-degree relatives (SRs), in whom milder forms of deficits reported in schizophrenia
Pinna, Federica, Gibertoni, D., Aguglia E., Amore M, Italian Network for Research on Psychoses., Marchesi C, Mucci, A., Goracci, A., Comparelli A, Gibertoni D., Rossi, A., Siracusano A, Rossi A, Aguglia, E., Vita A, Roncone, Rita, Amore, Mario, Maj, Mario, Rocca, P., Roncone, R., Di Giannantonio, M., Chieffi M, Galderisi, S., Ossola P., Monteleone, P., Stratta P., Roncone R, Galderisi S, Bucci, Paola, Maj M., Aguglia E, Amore, M., Montemagni, C., Comparelli, Anna, Bucci P., Montemagni, Cristiana, Monteleone, Palmiero, Goracci A, Di Giannantonio M., Goracci A., Pinna F., Zeppegno, P., Marchesi C., Bucci, P., Pinna F, Vita, A., Rucci P, Aguglia, Eugenio, Rocca, Paola, Rocca P., Rossi, Alessandro, Comparelli, A., Rocca P, GORACCI, ARIANNA, Siracusano, A., Blasi G, Maj M, Monteleone P, Siracusano A., Rucci, Paola, Stratta, Paolo, Rucci P., Rossi A., Monteleone P., Montemagni C, Gibertoni, Dino, Di Giannantonio M, Maj, M., Torti MC, Blasi, Giuseppe, Marchesi, C., Chieffi, M., Montemagni C., Chieffi, Marcello, Stratta, P., Mucci A, Torti, Maria Chiara, Rucci, P., Zeppegno, Patrizia, Stratta P, Vita A., Bertolino A, Blasi G., Bucci P, Pinna, F., Mucci A., Roncone R., Marchesi, Carlo, Torti M. C., Amore M., Zeppegno P, Comparelli A., Galderisi, Silvana, Vita, Antonio, Galderisi S., Di Giannantonio, Massimo, Bertolino A., Bertolino, Alessandro, Chieffi M., Torti, M. C., Gibertoni D, Psychoses, Italian Network for Research on Psychoses, Mucci, Armida, Zeppegno P., Siracusano, Alberto, Zeppegno, P, Montefusco, V, Carmine, Tomasetti, Mariangela, Rocco, Rocco, M, Di Giannantonio, M, Oldani, L, Giuseppe, Piegari, Di Emidio, G, Roncone, R, Niolu, C, Bernardo, Carpiniello, Paolo, Ossola, Tomasetti, C, Roberto, Brugnoli, Valentina, Montefusco, Rucci, P, Monteleone, P, Torti, M, Bucci, P, Marchesi, C, Laura, Giusti, Piegari, G, Tiziana, Frieri, Merlotti, E, Elena, Tenconi, Bolognesi, S, Aguglia, E, Gibertoni, D, Ossola, P, Brugnoli, R, Blasi, G, Patrizia, Zeppegno, Matteo, Respino, Campana, T, Teresa, Campana, Stefano, Barlati, Luca, Bartoli, Acciavatti, T, Barlati, S, Carpiniello, B, Comparelli, A, Montemagni, C, Giuseppe, Plescia, Maria Salvina, Signorelli, Maj, M, BELLOMO, ANTONELLO, Amore, M, Bellomo, A, NIOLU, CINZIA, Stratta, P, Tiziano, Acciavatti, Chieffi, M, Tenconi, E, Cinzia, Niolu, Gabriella, Di Emidio, Frieri, T., Siracusano, A, Dell'Osso, L, Liliana, Dell'Osso, Goracci, A, Bertolino, A, Respino, M, Porcelli, S, Bartoli, L, Lucio, Oldani, Pinna, F, Squarcione, C, Eleonora, Merlotti, Vita, A, Rocca, P, Chiara, Squarcione, Stefano, Porcelli, Mucci, A, Signorelli, M, Galderisi, S, Simone, Bolognesi, Rossi, A, Plescia, G, Frieri, T, Giusti, L   +185 more
core   +5 more sources

Hypertrophic cardiomyopathy in myosin-binding protein C (MYBPC3) Icelandic founder mutation carriers

Open Heart, 2020
ObjectiveThe myosin-binding protein C (MYBPC3) c.927-2A>G founder mutation accounts for >90% of sarcomeric hypertrophic cardiomyopathy (HCM) in Iceland.
Javier Diez, Begoña López, Barry J Maron, Berglind Adalsteinsdottir, Michael Burke, Ragnar Danielsen, Petr Jarolim, Jonathan Seidman, Christine E. Seidman, Carolyn Y Ho, Gunnar Th Gunnarsson   +10 more
doaj   +1 more source

Evaluating cognitive function in unaffected relatives of individuals with bipolar disorders: A meta-analysis

, 2022
Background: Available studies have evaluated cognition in the unaffected relatives of bipolar disorder patients; however, to our knowledge, there has been no quantitative analysis evaluating the foregoing association.
Jawad, Muhammad Youshay, Cao, Bing, Lui, Leanna M.W., Gill, Hartej, Ho, Roger C., Kwan, Angela Tian Hui, McIntyre, Roger S., Phan, Lee, Mansur, Rodrigo B., Gillissie, Emily S., Di Vencenzo, Joshua D., Krupski, Jillian R., Teopiz, Kayla M.   +12 more
core   +1 more source

COGNITIVE FUNCTIONS AND SCHIZOTYPAL TRAITS IN UNAFFECTED RELATIVES OF SCHIZOPHRENIA PATIENTS: NON-LINEAR EFFECTS OF FAMILIAL LOADING

Dialogues in Clinical Neuroscience & Mental Health, 2018
OBJECTIVE: Schizophrenia can be classified into familial and sporadic, according to the genetic loading carried. The comparison of unaffected relatives with familial (“multiplex”) vs.
C Ζouraraki, L Κaragiannopoulou, P Κaramaouna, SG Giakoumaki   +3 more
doaj   +1 more source

Increased Prevalence of Minor Physical Anomalies Among the Healthy First-Degree Relatives of Bipolar I Patients – Results With the Méhes Scale

Frontiers in Psychiatry, 2021
Minor physical anomalies are somatic markers of aberrant neurodevelopment, so the higher prevalence of these signs among the relatives of bipolar I patients can confirm minor physical anomalies as endophenotypes.
Tímea Csulak, Györgyi Csábi, Róbert Herold, Viktor Vörös, Sára Jeges, András Hajnal, Márton Áron Kovács, Maria Simon, Márton Herold, Ákos Levente Tóth, Tamás Tényi   +10 more
doaj   +1 more source

Knowledge about Essential Tremor: A Study of Essential Tremor Families

Frontiers in Neurology, 2018
BackgroundEssential tremor (ET) is among the most common neurological diseases and it often runs in families. How knowledgeable ET patients and their families are about their disease has been the subject of surprisingly little scholarship.MethodsTo fill ...
Ashley D. Cristal, Karen P. Chen, Nora Cristina Hernandez, Pam Factor-Litvak, Lorraine N. Clark, Lorraine N. Clark, Ruth Ottman, Ruth Ottman, Ruth Ottman, Ruth Ottman, Elan D. Louis, Elan D. Louis, Elan D. Louis   +12 more
doaj   +1 more source

Revealing a brain network endophenotype in families with idiopathic generalised epilepsy.

PLoS ONE, 2014
Idiopathic generalised epilepsy (IGE) has a genetic basis. The mechanism of seizure expression is not fully known, but is assumed to involve large-scale brain networks. We hypothesised that abnormal brain network properties would be detected using EEG in
Fahmida A Chowdhury, Wessel Woldman, Thomas H B FitzGerald, Robert D C Elwes, Lina Nashef, John R Terry, Mark P Richardson   +6 more
doaj   +1 more source

Exome sequencing of multiple-sclerosis patients and their unaffected first-degree relatives

BMC Research Notes, 2017
Objectives The understanding of complex multifactorial diseases requires the availability of a variety of data for a large-number of affected individuals.
Sheila Garcia-Rosa, Maria Galli de Amorim, Renan Valieris, Vanessa Daccach Marques, Julio Cesar Cetrulo Lorenzi, Vania Balardin Toller, Guilherme Sciascia do Olival, Wilson Araújo da Silva Júnior, Israel Tojal da Silva, Amilton Antunes Barreira, Diana Noronha Nunes, Emmanuel Dias-Neto   +11 more
doaj   +1 more source