Results 11 to 20 of about 103,359 (288)

Abnormal frontoparietal synaptic gain mediating the P300 in patients with psychotic disorder and their unaffected relatives. [PDF]

Hum Brain Mapp, 2017
The “dysconnection hypothesis” of psychosis suggests that a disruption of functional integration underlies cognitive deficits and clinical symptoms. Impairments in the P300 potential are well documented in psychosis.
Díez Á, Ranlund S, Pinotsis D, Calafato S, Shaikh M, Hall MH, Walshe M, Nevado Á, Friston KJ, Adams RA, Bramon E.   +10 more
europepmc   +5 more sources

Default Mode Network Aberrant Connectivity Associated with Neurological Soft Signs in Schizophrenia Patients and Unaffected Relatives [PDF]

Frontiers in Psychiatry, 2018
Brain connectivity and neurological soft signs (NSS) are reportedly abnormal in schizophrenia and unaffected relatives, suggesting they might be useful neurobiological markers of the illness.
Liliana Galindo, Liliana Galindo, Daniel Bergé, Daniel Bergé, Daniel Bergé, Graham K. Murray, Graham K. Murray, Graham K. Murray, Anna Mané, Anna Mané, Anna Mané, Antonio Bulbena, Antonio Bulbena, Victor Pérez, Victor Pérez, Victor Pérez, Oscar Vilarroya, Oscar Vilarroya   +17 more
doaj   +2 more sources

Failure to deactivate the default mode network indicates a possible endophenotype of autism [PDF]

Molecular Autism, 2012
Background Reduced activity during cognitively demanding tasks has been reported in the default mode network in typically developing controls and individuals with autism.
Spencer Michael D, Chura Lindsay R, Holt Rosemary J, Suckling John, Calder Andrew J, Bullmore Edward T, Baron-Cohen Simon   +6 more
doaj   +5 more sources

Abnormalities of localized connectivity in schizophrenia patients and their unaffected relatives: a meta-analysis of resting-state functional magnetic resonance imaging studies [PDF]

Neuropsychiatric Disease and Treatment, 2017
Bo Xiao, Shuai Wang, Jianbo Liu, Tiantian Meng, Yuqiong He, Xuerong Luo Mental Health Institute of the Second Xiangya Hospital, Central South University, National Clinical Research Center on Mental Health Disorders, National Technology Institute on ...
Xiao B, Wang S, Liu J, Meng T, He Y, Luo X   +5 more
doaj   +2 more sources

Anterior cingulate cortico-hippocampal dysconnectivity in unaffected relatives of schizophrenia patients: a stochastic dynamic causal modeling study [PDF]

Frontiers in Human Neuroscience, 2016
Familial risk plays a significant role in the etiology of schizophrenia (SZ). Many studies using neuroimaging have demonstrated structural and functional alterations in relatives of SZ patients, with significant results found in diverse brain regions ...
Yi-Bin Xi, Chen Li, Long-Biao Cui, Jian Liu, Fan Guo, Liang Li, Ping Tian, Ting-Ting Liu, Kang Liu, Gang Chen, Gang Chen, Min Xi, Hua-Ning Wang, Hong Yin   +13 more
doaj   +2 more sources

Dysbiosis of the faecal microbiota in patients with Crohn's disease and their unaffected relatives

Gut, 2011
Background and aims A general dysbiosis of the intestinal microbiota has been established in patients with Crohn's disease (CD), but a systematic characterisation of this dysbiosis is lacking.
Cnockaert, Margo, De Preter, Vicky, Huys, Geert, Joossens, Marie, Rutgeerts, Paul, Vandamme, Peter, Verbeke, Kristin, Vermeire, Severine   +7 more
core   +2 more sources

Associations between childhood maltreatment and oxidative nucleoside damage in affective disorders

European Psychiatry, 2022
Background Childhood maltreatment is an established risk factor for incident unipolar disorder and bipolar disorder. It is separately observed that affective disorders (AD) are also associated with higher nucleoside damage by oxidation.
Johanne Kofod Damm Eriksen, Klara Coello, Sharleny Stanislaus, Hanne Lie Kjærstad, Kimie Stefanie Ormstrup Sletved, Roger S. McIntyre, Maria Faurholt-Jepsen, Kamilla K. Miskowiak, Henrik Enghusen Poulsen, Lars Vedel Kessing, Maj Vinberg   +10 more
doaj   +1 more source

Differences in psychomotor activity and heart rate variability in patients with newly diagnosed bipolar disorder, unaffected relatives, and healthy individuals. [PDF]

J Affect Disord, 2020
Freyberg J, Brage S, Kessing LV, Faurholt-Jepsen M.   +3 more
europepmc   +2 more sources

Brain-derived neurotrophic factor levels in newly diagnosed patients with bipolar disorder, their unaffected first-degree relatives and healthy controls

BJPsych Open, 2021
Background Brain-derived neurotrophic factor (BDNF), which facilitates neuroplasticity and synaptogenesis, may be decreased in bipolar disorder, but has not been systematically investigated in people with newly diagnosed bipolar disorder and unaffected ...
Nanna Aagaard Petersen, Marc Østergaard Nielsen, Klara Coello, Sharleny Stanislaus, Sigurd Melbye, Hanne Lie Kjærstad, Kimie Stefanie Ormstrup Sletved, Roger S. McIntyre, Ruth Frikke-Smith, Maj Vinberg, Lars Vedel Kessing   +10 more
doaj   +1 more source

Impulsivity in unaffected adolescent biological relatives of schizophrenia patients [PDF]

Journal of Psychiatric Research, 2018
Although schizophrenia is not a prototypic impulse-control disorder, patients report more impulsive behaviors, have higher rates of substance use, and show dysfunction in brain circuits that underlie impulsivity. We investigate impulsivity in unaffected biological relatives of schizophrenia patients to further understand the relationships between ...
Beng-Choon, Ho, Amy B, Barry, Julie A, Koeppel   +2 more
openaire   +2 more sources