Results 111 to 120 of about 2,114,177 (304)

Supported employment adapted for people with affective disorders A randomized controlled trial

, 2017
Background While effective vocational methods for gaining employment exist for people with schizophrenia and similar conditions, no evidence exists with regard to people with affective disorders.
Bejerholm, Ulrika,, Johanson, Suzanne,, Lund University., Larsson, Maria E.,   +3 more
core   +2 more sources

Comparing the paths of Hedgehog release in artificial and natural settings

FEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

The metyrapone test in affective disorders and schizophrenia.

, 1984
The metyrapone test was applied to patients suffering from major depressive illness with melancholia, from mania, and from schizophrenia. Hypoactivity of the HPA axis as assessed by the test appears to occur infrequently in affective disorders and ...
Fava GA, Jusko WJ, Molnar G, Carson SW, Morphy MA, PERINI, GIULIA   +5 more
core  

Typology of hyperthymic personalities with affective phases

European Psychiatry
Introduction Modern authors characterize hyperthymic individuals as eloquent, humorous, self-confident, optimistic, energetic, liberated, sexually active, constantly planning and implementing their plans.
A. Barkhatova, A. Churkina, S. Sorokin
doaj   +1 more source

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

FEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini, Freia S. Buus, Benjamin Schuler, Birthe B. Kragelund   +3 more
wiley   +1 more source

The brief assessment of cognition in affective disorders: Normative data for the Italian population

, 2019
BACKGROUND: To date there are no validated tests in Italian to assess cognitive functions in Bipolar Disorder. Therefore, this study aimed to provide normative data for the Italian version of the Brief Assessment of Cognition in Affective Disorders (BAC-
Rossetti M. G., Perlini, Cinzia, Rossi R., Brambilla P., Porcelli S., Piccin S., Brambilla, Paolo, Perlini C., Porcelli, Stefano, Lanfredi M., Rossi, Roberta, Abbiati, Vera, Caletti E., Sala M., Rossetti, Maria Gloria, Bonivento, Carolina, Piccin, Sara, Lazzaretti, Matteo, Caletti, Elisabetta, Bellani, Marcella, Lanfredi, Mariangela, Marinelli, Veronica, Serretti A., Sala, Michela, Marinelli V., Serretti, Alessandro, Lazzaretti M., Bonivento C., Abbiati V., Garzitto, Marco, Garzitto M., Bellani M.   +31 more
core   +1 more source

Novel NSAID-Se derivative YSN-1-167 against Enterovirus 71 infection by inhibiting 3Dpol activity

Antimicrobial Agents and Chemotherapy
Hand, foot, and mouth disease (HFMD) is primarily caused by Enterovirus 71 (EV71) and Coxsackievirus A16 (CA16), while excessive inflammatory responses induced by viral infection are the main cause of severe conditions.
Yangxin Qi, Weiling Li, Qian Peng, Yingying Shi, Nan Tan, Yanrong Yang, Yinying Zhu, Song Hu, Bo Zhang, Pin Wan, Xiji Shu, Yuchen Liu, Liming Liu, Xianran He, Binlian Sun   +14 more
doaj   +1 more source

Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease

FEBS Letters, EarlyView.
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim, Thi Thanh Mai Tran, Nakyung Kang, Min‐Woo Lee, Mihye Lee   +4 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Synthesising 30 years of clinical experience and scientific insight on affective temperaments in psychiatric disorders: State of the art

The concept of affective temperament has been extensively discussed throughout the history of psychopathology and represents a cornerstone in the study of mood disorders.
Pessina, E., Brancati, G. E., Perugi, G., Bedani, F., Martiadis, V., Raffone, F., Cattaneo, C. I., Ressico, F., Martini, A., Pampaloni, I., Favaretto, E., De Berardis, D., Giovannini, S., Scarcella, L.   +13 more
core   +1 more source