Results 101 to 110 of about 245,119 (310)

Why are suicidal thoughts less prevalent in older age groups? Age differences in the correlates of suicidal thoughts in the English Adult Psychiatric Morbidity Survey 2007 [PDF]

, 2015
journaltitle: Journal of Affective Disorders date ...
Rantell, K, McManus, S, Cooper, C, Bebbington, P, Meltzer, H, Blanchard, M, Brugha, T, Dennis, M, Jenkins, R   +8 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Synthesising 30 years of clinical experience and scientific insight on affective temperaments in psychiatric disorders: State of the art [PDF]

The concept of affective temperament has been extensively discussed throughout the history of psychopathology and represents a cornerstone in the study of mood disorders.
Pessina, E., Brancati, G. E., Perugi, G., Bedani, F., Martiadis, V., Raffone, F., Cattaneo, C. I., Ressico, F., Martini, A., Pampaloni, I., Favaretto, E., De Berardis, D., Giovannini, S., Scarcella, L.   +13 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Light room therapy effective in mild forms of seasonal affective disorder - a randomised controlled study [PDF]

, 2008
BACKGROUND: The most common way to provide bright light therapy to Swedish patients with Seasonal Affective Disorder (SAD), is treatment in a light therapy room.
Ulfberg, Jan,, Rastad, Cecilia,, Lindberg, Per,   +2 more
core   +1 more source

SARS-CoV-2 Nsp7 plays a role in cognitive dysfunction by impairing synaptic plasticity

Frontiers in Neuroscience
It has been reported that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can result in long-term neurological symptoms such as cognitive dysfunction, however the specific mechanisms underlying this phenomenon remain unclear ...
Jiazheng Guo, WeiLing Li, Mengbing Huang, Jialu Qiao, Pin Wan, Yulin Yao, Lirui Ye, Ye Ding, Jianing Wang, Qian Peng, Wei Liu, Yiyuan Xia, Xiji Shu, Binlian Sun, Binlian Sun   +14 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Seasonal variation in affective disorders. A case register study [PDF]

, 1987
This paper reports the results of a study on seasonal variation in new episodes of affective disorders, conducted using the South-Verona psychiatric case register.
TANSELLA, Michele, BALESTRIERI, Matteo, P. Williams   +2 more
core  

Understanding individual and structural factors behind extensive care needs in personality disorders: an interpretative phenomenological analysis

Annals of General Psychiatry
Extensive care needs, including frequent hospitalizations and compulsory care, are common among individuals with personality disorders (PD), yet the outcomes of such interventions remain uncertain.
Jennifer Strand, Flavio Di Leone, Evelina Dervisoski, Parinazz Iranmanesh, Peter Sand   +4 more
doaj   +1 more source

Neural and Behavioral Predictors of Treatment Efficacy on Mood Symptoms and Cognition in Mood Disorders: A Systematic Review

Frontiers in Psychiatry, 2018
Background: The clinical and etiological heterogeneity of mood disorders impede identification of effective treatments for the individual patient. This highlights a need for early neuronal and behavioral biomarkers for treatment efficacy, which can ...
Ida Seeberg, Ida Seeberg, Hanne L. Kjaerstad, Kamilla W. Miskowiak, Kamilla W. Miskowiak   +4 more
doaj   +1 more source